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机译:<![CDATA [基于常规和细胞活性抑制剂的基于组的优化,von Hippel-lindau(VHL)E3泛素连接酶:结构 - 活性关系导致化学探针(2 S I>,4 R i>) - 1 - (( s i>) - 2-(1-氰基丙二丙烷羧酰甲酰amido)-3,3-dim]]>
Division of Biological Chemistry and Drug Discovery School of Life Sciences University of Dundee Dow Street Dundee DD1 5EH Scotland U.K.;
Division of Biological Chemistry and Drug Discovery School of Life Sciences University of Dundee Dow Street Dundee DD1 5EH Scotland U.K.;
Division of Biological Chemistry and Drug Discovery School of Life Sciences University of Dundee Dow Street Dundee DD1 5EH Scotland U.K.;
Division of Biological Chemistry and Drug Discovery School of Life Sciences University of Dundee Dow Street Dundee DD1 5EH Scotland U.K.;
Division of Biological Chemistry and Drug Discovery School of Life Sciences University of Dundee Dow Street Dundee DD1 5EH Scotland U.K.;
Division of Biological Chemistry and Drug Discovery School of Life Sciences University of Dundee Dow Street Dundee DD1 5EH Scotland U.K.;
Center for Gene Regulation and Expression School of Life Sciences University of Dundee Dow Street Dundee DD1 5EH Scotland U.K.;
Division of Biological Chemistry and Drug Discovery School of Life Sciences University of Dundee Dow Street Dundee DD1 5EH Scotland U.K.;
Division of Biological Chemistry and Drug Discovery School of Life Sciences University of Dundee Dow Street Dundee DD1 5EH Scotland U.K.;
机译:<![CDATA [基于常规和细胞活性抑制剂的基于组的优化,von Hippel-lindau(VHL)E3泛素连接酶:结构 - 活性关系导致化学探针(2 S I>,4 R i>) - 1 - (( s i>) - 2-(1-氰基丙二丙烷羧酰甲酰amido)-3,3-dim]]>
机译:基于片段的筛选和计算方法的表面探测识别von Hippel-Lindau(VHL)E3泛素连接酶上的可配脂袋
机译:开发选择性组蛋白脱乙酰酶6(HDAC6)降解剂募集von hippel-lindau(vhl)e3 ubiquitin连接酶
机译:基于组的优化和细胞活跃的概念von Hippel–Lindau(VHL)E3泛素连接酶的抑制剂:导致化学探针的结构-活性关系(2S4R)-1-((S)-2-(1-氰基环丙烷甲酰胺基)-33-二甲基丁酰基)-4-羟基-N-(4-(4-甲基噻唑-5-基)苄基)吡咯烷- 2-羧酰胺(VH298)
机译:基于组的von Hippel-Lindau(VHL)E3泛素连接酶有效和细胞活性抑制剂的优化:结构-活性关系导致化学探针(2S,4R)-1-((S)-2-(1 -氰基环丙烷甲酰胺基)-3,3-二甲基丁酰基)-4-羟基-N-(4-(4-甲基噻唑-5-基)苄基)吡咯烷-2-羧酰胺(VH298)