Effect of Haloperidol on Survival Among Critically Ill Adults With a High Risk of Delirium The REDUCE Randomized Clinical Trial

van den Boogaard Mark; Slooter Arjen J. C.; Bruggemann Roger J. M.; Schoonhoven Lisette; Beishuizen Albertus; Vermeijden J. Wytze; Pretorius Danie; de Koning Jan; Simons Koen S.; Dennesen Paul J. W.; Van der Voort Peter H. J.; Houterman Saskia; van der Hoeven J. G.; Pickkers Peter

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Effect of Haloperidol on Survival Among Critically Ill Adults With a High Risk of Delirium The REDUCE Randomized Clinical Trial

机译：Haloperidol对具有高风险的临床病人患者患者减少随机临床试验的危重成年人生存

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IMPORTANCE Results of studies on use of prophylactic haloperidol in critically ill adults are inconclusive, especially in patients at high risk of delirium.

机译：对预防性成年人的预防性氟哌啶醇的研究的重要性结果不确定，特别是谵妄风险高风险的患者。

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《JAMA: the Journal of the American Medical Association》 |2018年第7期|共11页
作者
van den Boogaard Mark; Slooter Arjen J. C.; Bruggemann Roger J. M.; Schoonhoven Lisette; Beishuizen Albertus; Vermeijden J. Wytze; Pretorius Danie; de Koning Jan; Simons Koen S.; Dennesen Paul J. W.; Van der Voort Peter H. J.; Houterman Saskia; van der Hoeven J. G.; Pickkers Peter;
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作者单位

Radboud Univ Nijmegen Med Ctr Dept Intens Care Med POB 9101 Internal Post 710 NL-6500 HB;

Univ Med Ctr Utrecht Dept Intens Care Med Utrecht Netherlands;

Radboud Univ Nijmegen Med Ctr Dept Pharm Nijmegen Netherlands;

Univ Southampton Fac Hlth Sci Southampton Hants England;

Med Spectrum Twente Dept Intens Care Med Enschede Netherlands;

Med Spectrum Twente Dept Intens Care Med Enschede Netherlands;

St Jansdal Hosp Harderwijk Dept Intens Care Med Harderwijk Netherlands;

Maxima Med Ctr Veldhoven Dept Intens Care Med Veldhoven Netherlands;

Jeroen Bosch Hosp Den Bosch Dept Intens Care Med Shertogenbosch Netherlands;

Haaglanden Med Ctr Dept Intens Care Med The Hague Netherlands;

Onze Lieve Vrouw Hosp Dept Intens Care Med Amsterdam Netherlands;

Onze Lieve Vrouw Hosp Dept Intens Care Med Amsterdam Netherlands;

Radboud Univ Nijmegen Med Ctr Dept Intens Care Med POB 9101 Internal Post 710 NL-6500 HB;

Radboud Univ Nijmegen Med Ctr Dept Intens Care Med POB 9101 Internal Post 710 NL-6500 HB;

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正文语种 eng
中图分类医药、卫生;
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1. Effect of Haloperidol on Survival Among Critically Ill Adults With a High Risk of Delirium The REDUCE Randomized Clinical Trial [J] . van den Boogaard Mark, Slooter Arjen J. C., Bruggemann Roger J. M., JAMA: the Journal of the American Medical Association . 2018,第7期

机译：Haloperidol对具有高风险的临床病人患者患者减少随机临床试验的危重成年人生存
2. Dexmedetomidine Reduces the Risk of Delirium, Agitation and Confusion in Critically Ill Patients: A Meta-analysis of Randomized Controlled Trials [J] . Pasin Laura, Landoni Giovanni, Nardelli Pasquale, Journal of cardiothoracic and vascular anesthesia . 2014,第6期

机译：右美托咪定可降低重症患者Deli妄，躁动和意识混乱的风险：一项随机对照试验的荟萃分析
3. Effect of rivastigmine as an adjunct to usual care with haloperidol on duration of delirium and mortality in critically ill patients: a multicentre, double-blind, placebo-controlled randomised trial [J] . MM Van Eijk, KC Roes, ML Honing, Critical care : . 2011,第Suppla1期

机译：利凡斯的明作为氟哌啶醇的常规护理的辅助措施，对重症患者的ir妄持续时间和死亡率的影响：一项多中心，双盲，安慰剂对照的随机试验
4. The Role of Probiotics in Inflammatory Responses of Critically-Ill Burn Patients (A Randomized Clinical Trial) [C] . Oki Nugraha Putra, Hengky Pebrianton, Suharjono, Health Science International Conference . 2017

机译：益生菌在危险性烧伤患者炎症反应中的作用（随机临床试验）
5. Educational intervention in adult asthma: A randomized clinical trial to determine if adult with asthma can learn how to use a Metered Dose Inhaler (MDI). [D] . Acosta, Juan. 2009

机译：成人哮喘的教育干预：一项随机临床试验，用于确定成人哮喘是否可以学习如何使用计量吸入器（MDI）。
6. Effect of haloperidol on survival among critically ill adults with a high risk of delirium: The REDUCE randomised controlled trial [O] . 2019

机译：氟哌啶醇对with妄高危危重成年人生存的影响：REDUCE随机对照试验
7. Effect of haloperidol on survival among critically ill adults with a high risk of delirium: The REDUCE randomised controlled trial [O] . 2018

机译：Haloperidol对具有高谵妄风险的批判性成年人中生存的影响：减少随机对照试验

Effect of Haloperidol on Survival Among Critically Ill Adults With a High Risk of Delirium The REDUCE Randomized Clinical Trial

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