Differences in Predictive Factors for Sustained Clinical Remission with Abatacept Between Younger and Elderly Patients with Biologic-naive Rheumatoid Arthritis: Results from the ABROAD Study

Sekiguchi Masahiro; Fujii Takao; Matsui Kiyoshi; Murakami Kosaku; Morita Satoshi; Ohmura Koichiro; Kawahito Yutaka; Nishimoto Norihiro; Mimori Tsuneyo; Sano Hajime

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Differences in Predictive Factors for Sustained Clinical Remission with Abatacept Between Younger and Elderly Patients with Biologic-naive Rheumatoid Arthritis: Results from the ABROAD Study

机译：持续临床缓解因素的差异与生物学 - 幼状类风湿性关节炎的年轻和老年人患者的持续临床缓解：来自国外研究的结果

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摘要

Objective. To differentiate predictive factors for sustained clinical remission between elderly and younger patients with rheumatoid arthritis (RA) receiving abatacept (ABA) as an initial biological disease-modifying antirheumatic drug.

机译：客观的。为了区分预测因素，以持续临床缓解持续临床缓解类风湿性关节炎（RA）接受Abatacept（ABA）作为初始生物疾病改性的抗胃酸药物。

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来源
《The Journal of rheumatology》 |2016年第11期|共10页
作者
Sekiguchi Masahiro; Fujii Takao; Matsui Kiyoshi; Murakami Kosaku; Morita Satoshi; Ohmura Koichiro; Kawahito Yutaka; Nishimoto Norihiro; Mimori Tsuneyo; Sano Hajime;
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作者单位

Hyogo Coll Med Dept Internal Med Div Rheumatol 1-1 Mukogawa Cho Nishinomiya Hyogo 6638501;

Kyoto Univ Grad Sch Med Kyoto Japan;

Hyogo Coll Med Nishinomiya Hyogo 6638501 Japan;

Kyoto Univ Grad Sch Med Kyoto Japan;

Kyoto Univ Grad Sch Med Kyoto Japan;

Kyoto Prefectural Univ Med Grad Sch Med Sci Kyoto Japan;

Osaka Rheumatol Clin Osaka Japan;

Kyoto Univ Grad Sch Med Kyoto Japan;

Hyogo Coll Med Dept Internal Med Div Rheumatol 1-1 Mukogawa Cho Nishinomiya Hyogo 6638501;

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原文格式 PDF
正文语种 eng
中图分类免疫性疾病;
关键词
RHEUMATOID ARTHRITIS; ABATACEPT; CLINICAL REMISSION; METHOTREXATE; ANTICITRULLINATED PROTEIN ANTIBODIES; HEALTH ASSESSMENT QUESTIONNAIRE-DISABILITY INDEX;

机译：类风湿性关节炎;ABATACEPT;临床缓解;甲氨蝶呤;抗谷氨酸蛋白抗体;健康评估问卷 - 残疾指数;

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专利

1. Differences in Predictive Factors for Sustained Clinical Remission with Abatacept Between Younger and Elderly Patients with Biologic-naive Rheumatoid Arthritis: Results from the ABROAD Study [J] . Sekiguchi Masahiro, Fujii Takao, Matsui Kiyoshi, The Journal of rheumatology . 2016,第11期

机译：初生和初生的类风湿性关节炎的年轻和老年人患者的Abatacept持续临床缓解的预测因素差异：ABROAD研究的结果
2. Attainment and characteristics of clinical remission according to the new ACR-EULAR criteria in abatacept-treated patients with early rheumatoid arthritis: new analyses from the Abatacept study to Gauge Remission and joint damage progression in methotrexate (MTX)-naive patients with Early Erosive rheumatoid arthritis (AGREE) [J] . Josef S. Smolen, Jürgen Wollenhaupt, Juan J. Gomez-Reino, Arthritis Research . 2015,第1期

机译：根据新的ACR-EULAR标准，在接受abatacept治疗的早期类风湿性关节炎患者中达到和达到临床缓解的特征：从Abatacept研究到未接受甲氨蝶呤（MTX）的早期侵蚀性类风湿性关节炎患者的量表缓解和关节损伤进展的新分析（同意）
3. Attainment and characteristics of clinical remission according to the new ACR-EULAR criteria in abatacept-treated patients with early rheumatoid arthritis: new analyses from the Abatacept study to Gauge Remission and joint damage progression in methotrexate (MTX)-naive patients with Early Erosive rheumatoid arthritis (AGREE) [J] . Josef S. Smolen, Jürgen Wollenhaupt, Juan J. Gomez-Reino, Arthritis research & therapy. . 2015,第Mara期

机译：临床缓解的临床缓解的临床缓解患者的早期类风湿性关节炎患者的新分析：从逐步的研究中的新分析，甲氨蝶呤（MTX）的甲氨蝶呤（MTX）的关节损伤进展 - 患者早期腐蚀类风湿性关节炎患者（同意）
4. Early disease control by low-dose prednisone comedication may affect the quality of remission In patients with early rheumatoid arthritis [C] . Monica Todoerti, Carlo Alberto Scire, Nicola Boffini, International Conference on the Neuroendocrine Immune Basis of the Rheumatic Diseases . 2010

机译：低剂量泼尼松的早期疾病控制可能会影响早期类风湿性关节炎患者的缓解质量
5. Clinical studies of immunomodulatory activities of Yunzhi -Danshen in breast cancer and nasopharyngeal carcinoma patients, and Lingzhi-San Miao San in rheumatoid arthritis patients. [D] . Bao, Yixi. 2005

机译：云芝丹参对乳腺癌和鼻咽癌患者及类风湿关节炎灵芝三妙散的免疫调节活性的临床研究。
6. Attainment and characteristics of clinical remission according to the new ACR-EULAR criteria in abatacept-treated patients with early rheumatoid arthritis: new analyses from the Abatacept study to Gauge Remission and joint damage progression in methotrexate (MTX)-naive patients with Early Erosive rheumatoid arthritis (AGREE) [O] . Josef S. Smolen, Jürgen Wollenhaupt, Juan J. Gomez-Reino, 2015

机译：根据新的ACR-EULAR标准在接受abatacept治疗的早期类风湿性关节炎患者中实现临床缓解的特征：从Abatacept研究到未接受甲氨蝶呤（MTX）的早期侵蚀性类风湿关节炎患者的量表缓解和关节损伤进展的新分析（同意）
7. Attainment and characteristics of clinical remission according to the new ACR-EULAR criteria in abatacept-treated patients with early rheumatoid arthritis: new analyses from the Abatacept study to Gauge Remission and joint damage progression in methotrexate (MTX)-naive patients with Early Erosive rheumatoid arthritis (AGREE) [O] . Josef S. Smolen, Jürgen Wollenhaupt, Juan J. Gomez-Reino, 2015

机译：根据新的ACR-EULAR标准在早期接受类风湿关节炎的阿巴西普治疗患者中的临床缓解的实现情况和特征：从Abatacept研究到未接受甲氨蝶呤（MTX）的早期侵蚀性类风湿关节炎患者的量表缓解和关节损伤进展的新分析（同意）

Differences in Predictive Factors for Sustained Clinical Remission with Abatacept Between Younger and Elderly Patients with Biologic-naive Rheumatoid Arthritis: Results from the ABROAD Study

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