Safety and Efficacy of a Novel Microbial Lipase in Patients with Exocrine Pancreatic Insufficiency due to Cystic Fibrosis: A Randomized Controlled Clinical Trial

Heubi James E.; Schaeffer David; Ahrens Richard C.; Sollo Natalie; Strausbaugh Steven; Graff Gavin; Jain Raksha; Witte Stephan; Forssmann Kristin

首页> 外文期刊>The Journal of pediatrics >Safety and Efficacy of a Novel Microbial Lipase in Patients with Exocrine Pancreatic Insufficiency due to Cystic Fibrosis: A Randomized Controlled Clinical Trial

【24h】

Safety and Efficacy of a Novel Microbial Lipase in Patients with Exocrine Pancreatic Insufficiency due to Cystic Fibrosis: A Randomized Controlled Clinical Trial

机译：一种新型微生物脂肪酶在囊性纤维化引起的胰腺功能不全的患者中的安全性和疗效：随机对照临床试验

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

团队文献服务 >>

页面导航

摘要
著录项
引文网络
相似文献
相关主题

摘要

Objective To evaluate the safety and efficacy of a novel microbial lipase (NM-BL) in a liquid formulation for the treatment of exocrine pancreatic insufficiency (EPI) in patients with cystic fibrosis (CF) in a phase IIa proof-of-concept study.

机译：目的探讨一种新型微生物脂肪酶（NM-BL）在液体纤维化（CF）患者患者中患者液体制剂中的一种新型微生物脂肪酶（NM-BL）的安全性和有效性。

著录项

来源
《The Journal of pediatrics》 |2016年第2016期|共7页
作者
Heubi James E.; Schaeffer David; Ahrens Richard C.; Sollo Natalie; Strausbaugh Steven; Graff Gavin; Jain Raksha; Witte Stephan; Forssmann Kristin;
展开▼
作者单位

Cincinnati Childrens Hosp Med Ctr Cincinnati OH 45229 USA;

Nemours Childrens Clin Jacksonville FL USA;

Univ Iowa Roy J &

Lucille A Carver Coll Med Iowa City IA USA;

Univ Kansas Sch Med Wichita Via Christi Res Wichita KS 67214 USA;

Rainbow Babies &

Childrens Hosp Cleveland OH 44106 USA;

Penn State Milton S Hershey Med Ctr Hershey PA USA;

Univ Texas Southwestern Med Ctr Dallas Dallas TX 75390 USA;

Nordmark Arzneimittel GmbH &

Co KG Uetersen Germany;

Nordmark Arzneimittel GmbH &

Co KG Uetersen Germany;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类儿科学;
关键词

相似文献

外文文献
中文文献
专利

1. Safety and Efficacy of a Novel Microbial Lipase in Patients with Exocrine Pancreatic Insufficiency due to Cystic Fibrosis: A Randomized Controlled Clinical Trial [J] . Heubi James E., Schaeffer David, Ahrens Richard C., The Journal of pediatrics . 2016,第期

机译：一种新型微生物脂肪酶在囊性纤维化引起的胰腺功能不全的患者中的安全性和疗效：随机对照临床试验
2. Randomised clinical trial: The efficacy and safety of pancreatin enteric-coated minimicrospheres (Creon 40000 MMS) in patients with pancreatic exocrine insufficiency due to chronic pancreatitis - A double-blind, placebo-controlled study [J] . ThoratV., ReddyN., BhatiaS., Alimentary pharmacology & therapeutics. . 2012,第5期

机译：随机临床试验：胰酶肠溶微球（Creon 40000 MMS）在慢性胰腺炎引起的胰腺外分泌功能不全患者中的有效性和安全性-一项双盲，安慰剂对照研究
3. Randomised clinical trial: the efficacy and safety of pancreatin enteric-coated minimicrospheres (Creon 40000 MMS) in patients with pancreatic exocrine insufficiency due to chronic pancreatitis - a double-blind, placebo-controlled study [J] . V. Thorat, N. Reddy, S. Bhatia, Alimentary Pharmacology & Therapeutics . 2012,第5期

机译：随机临床试验：胰酶肠溶微球（Creon 40000 MMS）在慢性胰腺炎引起的胰腺外分泌功能不全患者中的有效性和安全性-一项双盲，安慰剂对照研究
4. The Proteomic Analysis of Pancreatic Exocrine Insufficiency Protein Marker in Type 2 Diabetes Mellitus Patients [C] . Arie Srihardyastutie, D W Soeatmadji, Fatchiyah International Conference on Chemistry and Material Science . 2018

机译：2型糖尿病患者胰腺外蛋白蛋白标志物的蛋白质组学分析
5. Assessing pancreatic enzyme efficacy in patients with cystic fibrosis: Evaluation of a combination approach using unprotected pancreatic enzymes and pH-sensitive enteric-coated microspheres. [D] . Kalnins, Daina Brigita. 2003

机译：评估囊性纤维化患者的胰酶功效：使用未保护的胰酶和pH敏感的肠溶微球的组合方法评估。
6. Randomised clinical trial: the efficacy and safety of pancreatin enteric-coated minimicrospheres (Creon 40000 MMS) in patients with pancreatic exocrine insufficiency due to chronic pancreatitis - a double-blind placebo-controlled study [O] . V Thorat, N Reddy, S Bhatia, -1

机译：一项随机临床试验：胰酶肠溶微球（Creon 40000 MMS）在慢性胰腺炎引起的胰腺外分泌功能不全患者中的有效性和安全性-一项双盲安慰剂对照研究
7. Corrigendum to “Efficacy and safety of PANCREAZE® for treatment of exocrine pancreatic insufficiency due to cystic fibrosis” J Cyst Fibros, 10(2011)350-356 [O] . Trapnell Bruce C., Strausbaugh Steven D., Woo Marlyn S., 2011

机译：“PANCREAZE®治疗因囊性纤维化引起的外分泌性胰腺功能不全的疗效和安全性”更正J Cyst Fibros，10（2011）350-356

Safety and Efficacy of a Novel Microbial Lipase in Patients with Exocrine Pancreatic Insufficiency due to Cystic Fibrosis: A Randomized Controlled Clinical Trial

摘要

著录项

引文网络

相似文献

相关主题

期刊订阅