<![CDATA[An efficient in-situ reduction and cyclization reaction for the synthesis of 9-aryl-1,6,8,9-tetrahydro-7 <ce:italic>H</ce:italic>-pyrazolo[3,4- <ce:italic>f</ce:italic>]quinolin-7-one, 11-aryl-1,6,7,8,9,11-hexahydro-10 <ce:italic>H</ce:italic>-pyrazolo [3,4- <ce:italic>a</ce:italic>]acridin-10-one, and 11-aryl-3,6,7,8,9,11-hexahydro-10 <ce:italic>H</ce:italic>-imidazo[4,5- <ce:italic>a</ce:italic>]acridin-10-one derivatives]]>

Lirong Yan; Qingyang Li; Hui Xu; Zhongyun Xu; Qiuyu Yu; Yaqi Qin; Liangce Rong

首页> 外文期刊>Tetrahedron >H-pyrazolo[3,4- f]quinolin-7-one, 11-aryl-1,6,7,8,9,11-hexahydro-10 H-pyrazolo [3,4- a]acridin-10-one, and 11-aryl-3,6,7,8,9,11-hexahydro-10 H-imidazo[4,5- a]acridin-10-one derivatives]]>

【24h】

H-pyrazolo[3,4- f]quinolin-7-one, 11-aryl-1,6,7,8,9,11-hexahydro-10 H-pyrazolo [3,4- a]acridin-10-one, and 11-aryl-3,6,7,8,9,11-hexahydro-10 H-imidazo[4,5- a]acridin-10-one derivatives]]>

机译：<！[CDATA [效率的原位还原和用于合成9-芳基-1,6,8,9-四氢-7的循环化反应：斜体> H -Pyrazolo [3， 4- f ]喹啉-7-one，11-芳基-1,6,7,8,9,11-六羟基-10 h -Pyrazolo [3,4- a ]吖啶-10-一，11-芳基-3,6,7,8,9,11-hexahydro-10 h -4,5- a ]吖啶-10-一个衍生物]]>

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Abstract

An efficient in-situ reduction and cyclization reaction was reported from the aromatic aldehydes, 6-nitro-1H-indazole (5-nitrobenzimidazole), and 2,2-dimethyl-1,3-dioxane-4,6-dione (1,3-cyclohexanedione or dimedone) to synthesize 9-aryl-1,6,8,9-tetrahydro-7H-pyrazolo[3,4-f]quinolin-7-one, 11-aryl-1,6,7,8,9,11-hexahydro-10H-pyrazolo [3,4-a]acridin-10-one, and 11-aryl-3,6,7,8,9,11-hexahydro-10H-imidazo[4,5-a]acridin-10-one derivatives in the presence of SnCl2·2H2O in THF medium. The advantages of this method are mild conditions, convenient manipulation, high yields and wide range of substrates.

Graphical abstract

Display Omitted

]]>

机译：<！[CDATA [ 抽象一种有效的原位还原和环化反应从芳香醛报道，6-硝基 - 1 ħ - 吲唑（5-硝基苯并咪唑），和2,2-二甲基-1,3-二恶烷-4,6-二酮（1,3-环己二酮或双甲酮），以合成9 - 芳基-1,6,8,9四氢-7- ħ - 吡唑并[3,4 ˚F]喹啉-7-酮， 11芳基1,6,7,8,9,11六氢10 ħ - 吡唑并[3,4 一 ]吖啶-10-酮，和11-芳基3,6,7,8,9,11六氢10 ħ - 咪唑并[4,5-一]吖啶-10-酮在的SnCl 2 ·2H 2 0在THF平台。这种方法的优点是在温和的条件，操作方便，高的产率和宽范围的底物图形抽象显示中省略 ]]>

著录项

来源
《Tetrahedron》 |2017年第48期|共10页
作者
Lirong Yan; Qingyang Li; Hui Xu; Zhongyun Xu; Qiuyu Yu; Yaqi Qin; Liangce Rong;
展开▼
作者单位

Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials School of Chemistry and Materials Science Jiangsu Normal University;

Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials School of Chemistry and Materials Science Jiangsu Normal University;

Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials School of Chemistry and Materials Science Jiangsu Normal University;

Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials School of Chemistry and Materials Science Jiangsu Normal University;

Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials School of Chemistry and Materials Science Jiangsu Normal University;

Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials School of Chemistry and Materials Science Jiangsu Normal University;

Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials School of Chemistry and Materials Science Jiangsu Normal University;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类化学;
关键词
Pyrazolo3; 4-fquinoline; Imidazo4; 5-aacridin-10-one; In-situ reduction; 6-Nitro-1H-indazole; 5-Nitrobenzimidazole;

机译：Pyrazolo [3;4-f]喹啉;咪唑[4;5-A]吖啶-10-一;原位还原;6-硝基-1H-吲唑;5-硝基苯咪唑;

相似文献

外文文献
专利

1. H-pyrazolo[3,4- f]quinolin-7-one, 11-aryl-1,6,7,8,9,11-hexahydro-10 H-pyrazolo [3,4- a]acridin-10-one, and 11-aryl-3,6,7,8,9,11-hexahydro-10 H-imidazo[4,5- a]acridin-10-one derivatives]]> [J] . Lirong Yan, Qingyang Li, Hui Xu, Tetrahedron . 2017,第48期

机译：<！[CDATA [效率的原位还原和用于合成9-芳基-1,6,8,9-四氢-7的循环化反应：斜体> H -Pyrazolo [3， 4- f ]喹啉-7-one，11-芳基-1,6,7,8,9,11-六羟基-10 h -Pyrazolo [3,4- a ]吖啶-10-一，11-芳基-3,6,7,8,9,11-hexahydro-10 h -4,5- a ]吖啶-10-一个衍生物]]>
2. H-pyrazolo[4,3- c]pyridine-3,4(5 H)-diones]]> [J] . Gary Fairley, Ryan Greenwood, Caroline Anne McMillan Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2018,第39期

机译：<！[cdata [单盆合成新型1,2,6,7-四氢-3 h -pyrazolo [4,3- c ]吡啶-3,4（5 H ） - 致密]]>
3. maloNHC)]-catalyzed synthesis of 2-aryl pyrazolo[5,1- a]isoquinolines by annulation of N′-(2-((trimethylsilyl)ethynyl)benzylidene)hydrazides with terminal aromatic alkynes]]> [J] . Huixin Liu, Le Lu, Ruimao Hua Tetrahedron . 2017,第45期

机译：<！[cdata [[cu（ malo nhc）] - 催化合成2-芳基吡唑的合成[5,1- a斜体>]异喹啉通过将 n ' - （2 - （（（三甲基甲硅烷基）乙炔基）苄基）苯三苯基）]]]>
4. The Development of Hanwen Regular Script and Its Influence on Italic Typography [C] . Zhengying Wang International Conference on Art Studies: Science, Experience, Education . 2019

机译：汉文常规剧本的发展及其对斜体排版的影响
5. Synthesis of 2,3,4,4A,9,10-hexahydro-7-methoxy-4A-methylphenanthren-2-one by aryl radical cyclization. Studies directed toward the asymmetric total synthesis of (+)-cepharamine. Asymmetric and racemic syntheses, opioid receptor affinities, and antinociceptive effects of a new class of structural analogues of the morphine alkaloids. [D] . Wang, Aihua. 1997

机译：通过芳基环化反应合成2,3,4,4A，9,10-六氢-7-甲氧基-4A-甲基菲-2-研究针对（+）-头孢拉明的不对称全合成。非对称和外消旋的合成，阿片受体的亲和力以及吗啡生物碱的新型结构类似物的镇痛作用。
6. Transcriptome and DNA methylome reveal insights into yield heterosis in the curds of broccoli (Brassica oleracea L var. italic) [O] . Hui Li, Jiye Yuan, Mei Wu, 2018

机译：转录组和DNA甲基化组揭示了对西兰花凝乳（Brassica oleracea L var.italic）的产量杂种优势的见解。
7. Myh11R247C/R247C mutations increase thoracic aorta vulnerability to intramural damage despite a general biomechanical adaptivity [O] . Chiara Bellini, Shanzhi Wang, Dianna M. Milewicz, 2015

机译： myh 11 R 247 C / R 247 C 突变将胸部主动脉漏洞增加到INT休耕损伤尽管是一般的生物力学适应性

H-pyrazolo[3,4- f]quinolin-7-one, 11-aryl-1,6,7,8,9,11-hexahydro-10 H-pyrazolo [3,4- a]acridin-10-one, and 11-aryl-3,6,7,8,9,11-hexahydro-10 H-imidazo[4,5- a]acridin-10-one derivatives]]>

摘要

著录项

相似文献

相关主题

期刊订阅