Synthesis and identification of metabolite biomarkers of 25C-NBOMe and 25I-NBOMe

Xiongyu Wu; Caroline Eriksson; Ariane Wohlfarth; Jakob Wallgren; Robert Kronstrand; Martin Josefsson; Johan Dahlén; Peter Konradsson

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Synthesis and identification of metabolite biomarkers of 25C-NBOMe and 25I-NBOMe

机译：25C-Nbome和25i-Nbome代谢物生物标志物的合成与鉴定

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Abstract

Synthetic routes have been developed for synthesis of potential metabolites of 25C-NBOMe and 25I-NBOMe. Nine potential metabolites have been synthesized, among which compounds8and20acould be used as metabolite biomarkers of 25C-NBOMe and20bof 25I-NBOMe in urinary detection at forensic laboratories to prove intake.

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机译：<！[CDATA [ 抽象合成路线已为25C-NBOMe和25I-NBOMe的潜在代谢物的合成显影。九种潜在代谢物已被合成，其中的化合物 8 和 20A 可以作为25C-NBOMe和 20b的 25I-NBOMe在法医实验室尿检测来证明摄取图形抽象显示中省略 ]]>

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来源
《Tetrahedron》 |2017年第45期|共8页
作者
Xiongyu Wu; Caroline Eriksson; Ariane Wohlfarth; Jakob Wallgren; Robert Kronstrand; Martin Josefsson; Johan Dahlén; Peter Konradsson;
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作者单位

Department of Physics Chemistry and Biology Link?ping University;

Department of Physics Chemistry and Biology Link?ping University;

Department of Forensic Genetics and Forensic Toxicology National Board of Forensic Medicine;

Department of Physics Chemistry and Biology Link?ping University;

Department of Forensic Genetics and Forensic Toxicology National Board of Forensic Medicine;

Department of Forensic Genetics and Forensic Toxicology National Board of Forensic Medicine;

Department of Physics Chemistry and Biology Link?ping University;

Department of Physics Chemistry and Biology Link?ping University;

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原文格式 PDF
正文语种 eng
中图分类化学;
关键词
Biomarker; 25C-NBOMe; 25I-NBOMe; Metabolite; Urinary detection;

机译：生物标志物;25c-nbome;25i-nbome;代谢物;尿辨率检测;

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1. Synthesis and identification of metabolite biomarkers of 25C-NBOMe and 25I-NBOMe [J] . Xiongyu Wu, Caroline Eriksson, Ariane Wohlfarth, Tetrahedron . 2017,第45期

机译：25C-Nbome和25i-Nbome代谢物生物标志物的合成与鉴定
2. Identification of Metabolite Biomarkers of the Designer Hallucinogen 25I-NBOMe in Mouse Hepatic Microsomal Preparations and Human Urine Samples Associated with Clinical Intoxication [J] . Poklis Justin L., Dempsey Sara K., Liu Kai, Journal of Analytical Toxicology . 2015,第8期

机译：设计师幻觉原25I-NBOMe代谢物生物标志物在小鼠肝微粒体制剂和与临床中毒相关的人类尿液样品中的鉴定
3. Synthesis and identifications of potential metabolites as biomarkers of the synthetic cannabinoid AKB-48 [J] . Wallgren Jakob, Vikingsson Svante, Astrand Anna, Tetrahedron . 2018,第24期

机译：潜在代谢产物的合成及鉴定为合成大麻素AKB-48的生物标志物
4. Determination of an iNOS inhibitor with simultaneous metabolite identification and endogenous biomarker quantitation using high resolution orbitrap mass spectrometry [C] . John G Swales, Richard T Gallagher, Raimund M Peter American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：使用高分辨率横谱法鉴定具有同时代谢物鉴定和内源生物标志物定量的InOS抑制剂
5. Analysis of Novel Cyanide Antidote Dimethyl Trisulfide for Pharmacokinetic Studies, and Sulfur Mustard Metabolites for Identification of Biomarker of Inhaled Dose [D] . Manandhar, Erica. 2017

机译：新型氰化物解毒剂二甲基三硫化物的药代动力学研究与硫芥子油代谢物的吸入剂量生物标志物鉴定
6. Identification of Metabolite Biomarkers of the Designer Hallucinogen 25I-NBOMe in Mouse Hepatic Microsomal Preparations and Human Urine Samples Associated with Clinical Intoxication [O] . Justin L. Poklis, Sara K. Dempsey, Kai Liu, -1

机译：设计师幻觉原25I-NBOMe代谢物生物标志物在小鼠肝微粒体制剂和与临床中毒相关的人类尿液样品中的鉴定
7. Synthesis and identification of metabolite biomarkers of 25C-NBOMe and 25I-NBOMe [O] . Xiongyu Wu, Caroline Eriksson, Ariane Wohlfarth, 2017

机译：25C-Nbome和25i-Nbome代谢物生物标志物的合成与鉴定

Synthesis and identification of metabolite biomarkers of 25C-NBOMe and 25I-NBOMe

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