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首页> 外文期刊>Physics in medicine and biology. >Experimental characterization of lateral profiles of scanned proton and carbon ion pencil beams for improved beam models in ion therapy treatment planning.
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Experimental characterization of lateral profiles of scanned proton and carbon ion pencil beams for improved beam models in ion therapy treatment planning.

机译:离子治疗规划中改进梁模型扫描质子和碳离子铅束横向谱的实验表征。

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Scanned ion pencil beams carry a low-dose envelope which can extend up to several centimeters from the individual beam central axis. Depending on the energy and species of the beam, this halo consists mainly of secondary particles produced by nuclear interactions in the target or of particles undergoing multiple Coulomb scattering in the beam line components. This halo is often neglected by single Gaussian beam modeling in current treatment planning systems. One possibility of improving the accuracy of treatment planning is to upgrade the used pencil beam models by adding a description of the low-dose envelope. But at the same time it is crucial to keep the calculation time and the complexity for treatment planning in reasonable limits. As a first approach we measured the lateral beam profiles of scanned proton and carbon ion pencil beams at different energies and depths in water and air at the Heidelberg Ion Beam Therapy Center. Then we tried to describe their beam halo by adding a supplementary Gaussian function to the standard single Gauss modeling which is used at the moment by our treatment planning systems. This analysis helped to identify trends in the parameters describing the lateral beam broadening to support its modeling. Finally, it is shown that the accuracy of treatment planning could be improved by the proposed upgrade of the pencil beam model. In particular, the presented experimental data can be either used directly as input for dose calculation or serve for representative comparison with the results of calculation models such as Monte Carlo simulations for the generation of lateral basic data to be input in upgraded beam models of treatment planning systems.
机译:扫描的离子铅笔束携带低剂量包络,其可以从各个光束中心轴线延伸到几厘米。根据光束的能量和物种,该卤素主要由靶或在梁线组件中经历多个库仑散射的颗粒产生的核相互作用产生的二次粒子。该光环通常通过当前治疗计划系统中的单高斯光束建模忽略。提高治疗规划准确性的一种可能性是通过添加低剂量包络的描述来升级使用的铅笔梁模型。但同时保持计算时间和合理限制治疗计划的复杂性至关重要。作为第一方法,我们测量了在海德堡离子束治疗中心的不同能量和水中的扫描质子和碳离子铅笔梁的横向光束轮廓。然后,我们尝试通过向标准单个高斯建模添加补充高斯函数来描述它们的光束光环,这是我们的治疗计划系统使用的标准单个高斯建模。该分析有助于确定描述横向波束扩展以支持其建模的参数的趋势。最后,结果表明,通过铅笔梁模型的升级,可以提高治疗规划的准确性。特别地,所提出的实验数据可以直接用于剂量计算的输入,或者用于代表性比较,与计算模型的结果相比,例如Monte Carlo模拟,用于产生升级的升级的治疗计划的光束模型中的横向基本数据系统。

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