Amphiregulin promotes trophoblast invasion and increases MMP9/TIMP1 ratio through ERK1/2 and Akt signal pathways

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Amphiregulin promotes trophoblast invasion and increases MMP9/TIMP1 ratio through ERK1/2 and Akt signal pathways

机译：Amphiregulin促进滋养细胞侵入，通过ERK1 / 2和AKT信号途径增加MMP9 / TIMP1比率

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摘要

Aims: The aim of our study is to illustrate the role of amphiregulin in trophoblast invasiveness and underlying signal cascades.

机译：目的：我们的研究目的是说明Amphiregulin在滋养细胞侵袭和底层信号级联中的作用。

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《Life sciences 》 |2019年第2019期| 共11页
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正文语种 eng
中图分类医药、卫生 ;
关键词
Amphiregulin; HTR-8/SVneo cell; MMP9/TIMP-1 ratio; Invasiveness; ERK1/2; Akt;

机译：Amphiregulin;HTR-8 / Svneo细胞;MMP9 / TIMP-1比率;侵袭性;ERK1 / 2;AKT;

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1. Amphiregulin promotes trophoblast invasion and increases MMP9/TIMP1 ratio through ERK1/2 and Akt signal pathways [J] . Life sciences . 2019 ,第期

机译：Amphiregulin促进滋养细胞侵入，通过ERK1 / 2和AKT信号途径增加MMP9 / TIMP1比率
2. M2 macrophage‐derived G‐CSF promotes trophoblasts EMT, invasion and migration via activating PI3K/Akt/Erk1/2 pathway to mediate normal pregnancy [J] . Jinli Ding, Chaogang Yang, Yi Zhang, Journal of cellular and molecular medicine. . 2021 ,第4期

机译：M2巨噬细胞衍生的G-CSF通过激活PI3K / AKT / ERK1 / 2途径促进滋养细胞EMT，侵袭和迁移来调解正常怀孕
3. Chemokine CCL24 promotes the growth and invasiveness of trophoblasts through ERK1/2 and PI3K signaling pathways in human early pregnancy [J] . Hui Li, Yu-Han Meng, Wen-Qing Shang, Reproduction: The official journal of the Society for the Study of Fertility . 2015 ,第5期

机译：趋化因子CCL24通过人类早期妊娠中的ERK1 / 2和PI3K信号通路促进滋养细胞的生长和侵袭性
4. Lactoferrin induces the synthesis of vitamin B6 and protects HUVEC functions by activating PDXP and the PI3K/AKT/ERK1/2 pathway [C] . Y.Z.Wang, H.Y.Li, H.G.Yang, The 6th International Symposium on Dairy Cow Nutrition and Milk Quality（第六届“奶牛营养与牛奶质量”国际研讨会）论文集 . -1

机译：乳铁蛋白诱导维生素B6的合成，通过激活PDXP和PI3K / AKT / ERK1 / 2路径来保护HUVEC功能
5. Signaling pathway from the A(2B) adenosine receptor to extracellular signal-regulated kinases (ERK1/2) in human umbilical vein endothelial cells (HUVEC) and its role in HUVEC proliferation [D] . Fang, Ying 2006

机译：从A（2B）腺苷受体到人脐静脉内皮细胞（HUVEC）中细胞外信号调节激酶（ERK1 / 2）的信号通路及其在HUVEC增殖中的作用
6. The m6A-suppressed P2RX6 activation promotes renal cancer cells migration and invasion through ATP-induced Ca2+ influx modulating ERK1/2 phosphorylation and MMP9 signaling pathway [O] . Dongkui Gong, Jin Zhang, Yonghui Chen, 2019

机译：m6A抑制的P2RX6激活通过ATP诱导的Ca2 +内流调节ERK1 / 2磷酸化和MMP9信号通路促进肾癌细胞的迁移和侵袭
7. The m6A-suppressed P2RX6 activation promotes renal cancer cells migration and invasion through ATP-induced Ca2+ influx modulating ERK1/2 phosphorylation and MMP9 signaling pathway [O] . Dongkui Gong, Jin Zhang, Yonghui Chen, 2019

机译：通过ATP诱导的Ca2 +流入调节ERK1 / 2磷酸化和MMP9信号通路，M6A-抑制的P2RX6活化促进肾癌细胞迁移和侵袭

Amphiregulin promotes trophoblast invasion and increases MMP9/TIMP1 ratio through ERK1/2 and Akt signal pathways

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