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Integral quality monitor (IQM ? ? ) signal correction factors for small fields to predict larger irregular segment output signals

机译:积分质量监视器(IQM???)用于小字段的信号校正因子,以预测更大的不规则段输出信号

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摘要

Purpose To develop a method of correcting for the inaccuracies of small adjoined field segments in their contribution to larger fields in order to get a better match between their combined signals and the measured integral quality monitor (IQM) open field signals. This would enable the pre‐calculation of known irregular segment output signals per monitor unit (MU), which would be later useful for patient‐based dose calculations for treatment verification during pre‐treatment treatment validation using the IQM output signal per MU. Methods Small fields exhibit source obscurity and loss of scatter, resulting in smaller signals being measured by the IQM and the subsequent underestimation of IQM output signals of larger segments obtained by combining small segment signals. Larger field segments were broken down into a set of smaller, regular, abutted segments, whose individual signals were added together to get the predicted output signal of the larger field. The signal/MU for each smaller constituent segment was extracted at its exact location from measured IQM response maps, generated by irradiating the IQM with small elementary segments ranging from 1?×?1?cm 2 –5?×?5?cm 2 , shifting each segment 1?cm at a time and measuring its corresponding output signal/MU throughout the entire IQM sensitive area. The predicted signal was weighed against the IQM‐measured signal of the open field to calculate a signal correction factor (CF) of each elementary segment size. The CFs were applied to known signals of each set of elementary fields before summation in order to pre‐calculate signals of larger irregular fields more accurately. The dependence of CFs on elementary segment size, location of the open field, and beam energy was investigated. Results CFs exhibited an exponential decrease with increase in elementary segment size. CFs were also invariant with beam energy, changing by ≤1% from 6–15?MV. Uncorrected signals for regular fields had relative errors of above 5% whilst signal correction reduced these errors down to ~0.4% (i.e., 99.6% accuracy). For irregular fields, signal correction reduced calculation errors from ~10% to well below 1.5%. Larger signal prediction errors were found when smaller segments were used to reconstruct the field. Open field size and location had a great impact on measured signals but virtually no significance on CFs. Conclusions Results indicate that summation of small segment signals cannot sufficiently reproduce the same output given by an open field if individual elementary segment signals are not weighted with their respective CFs. This effect is particularly predominant for elementary segments 3?×?3?cm 2 and for irregular fields. The method outlined enabled the calculation of signal CFs in order to match predicted signals with measured signals to 98.5% accuracy, thus enabling the pre‐calculation of irregular segment output signals/MU for future patient dose calculations.
机译:目的是开发一种纠正对较大领域的小型邻接场段的不准确性的方法,以便在其组合信号和测量的整体质量监视器(IQM)开场信号之间获得更好的匹配。这将使每个监测单元(MU)的已知的不规则段输出信号的预先计算,这将在使用每亩的IQM输出信号进行预处理治疗验证期间的基于患者的剂量计算,这将是用于治疗验证的患者的剂量计算。方法采用小型字段表现出源杂乱无缺和散射损失,导致通过IQM测量的较小信号,随后通过组合小段信号而获得的较大段的IQM输出信号的较小信号。将更大的场段分解为一组较小的常规滞留段,其单独的信号被添加在一起以获得更大场的预测输出信号。通过测量的IQM响应图在其精确位置提取每个较小的组成部分的信号/亩,通过用1Ω×1Ωm2-5?×5?cm 2,一次将每个段1?CM移位并在整个IQM敏感区域中测量其相应的输出信号/ mu。预测信号被称为开放场的IQM测量信号,以计算每个基本段大小的信号校正因子(CF)。在总和之前将CFS应用于每组基本场的已知信号,以便更准确地预先计算更大的不规则字段的信号。研究了CFS对开放场和光束能量的基本段大小的依赖性。结果CFS随着基本段大小的增加,表现出指数下降。 CFS也不导致光束能量,从6-15°MV变化≤1%。对于常规字段的未校正信号具有高于5%的相对误差,而信号校正将这些误差降至约0.4%(即99.6%的精度)。对于不规则字段,信号校正将计算误差降低到10%,低于1.5%。当使用较小的段来重建场时,发现了较大的信号预测误差。开放场大小和位置对测量信号产生了很大影响,但在CFS上几乎没有意义。结论结果表明,如果单个基本段信号不加权,则小段信号的总和不能充分地再现由开放场给出的相同输出,如果单个基本的段信号没有加权它们各自的CF。对于基本段3?×3?3厘米2和不规则领域,这种效果特别主要。概述的方法使得信号CFS的计算为了匹配测量信号的预测信号至98.5%的精度,从而使不规则段输出信号/亩的预先计算用于未来的患者剂量计算。

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