[( parapara ‐Cymene)Ru(dppp)Cl][PF ₆6 ]‐Catalysed Stereospecific Synthesis of OO ‐Dienyl Esters, and Evaluation of the Anticancer Activity of a Long‐Chain Fatty Acid OO ‐Dienyl Ester

摘要

> O ‐Dienyl esters are obtained through the regio‐ and stereospecific addition of both aromatic and aliphatic carboxylic acids to terminal propargylic alcohols, with the sequential formation of a carbon–oxygen bond and dehydration, in the presence of [( p ‐cymene)Ru(dppp)Cl][PF ₆ ] ( 1 ). Also, the cytotoxicity and anticancer activity of the newly synthesized O ‐dienyl ester ( Z )‐3‐methylbuta‐1,3‐dienyl oleate have been investigated.