A new epidemics–logistics model: Insights into controlling the Ebola virus disease in West Africa

摘要

Highlights?A new integrated epidemics–logistics model to optimize logistics for an epidemic.?The model considers treatment capacity, migration, and spatial transmission rates.?Model predictions closely fit the real 2014–2015 Ebola outbreak case and death data.?Results provide information and insights on intervention timing, location, and intensity.?The model can be adopted to predict and control other infectious diseases.AbstractCompartmental models have been a phenomenon of studying epidemics. However, existing compartmental models do not explicitly consider the spatial spread of an epidemic and logistics issues simultaneously. In this study, we address this limitation by introducing a new epidemics–logistics mixed-integer programming (MIP) model