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The end of body composition methodology research?

机译:人体成分研究方法论的终结?

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PURPOSE OF REVIEW: Over one century of research has led to methods for measuring all major body components at the atomic, molecular, cellular, and tissue-system levels. These remarkable developments have fueled a rapid and sustained increase in 'body composition' biological findings and related publications. Other than small, incremental improvements in available methods, is there no longer a need for developing new body composition methods? This review examines the question: are we approaching the 'end' of body composition methodology research? RECENT FINDINGS: Emerging and rapidly growing areas outside of 'traditional' body composition research are highlighting the need for new and innovative method development. Recently introduced technologies such as positron emission tomography and functional magnetic resonance imaging extend 'mass' estimates to corresponding 'function' and physiology in humans. Although all major components are now measurable in humans, large gaps remain when considering factors such as radiation exposure, invasiveness, static versus dynamic measurements, and laboratory versus clinic and field assessments. SUMMARY: The end of the first phase of body composition method development has now arrived: all major components are measurable in vivo. The accessibility of these methods is stimulating rapid advances in biological knowledge surrounding human body composition from in utero to old age. Sustaining advances in new body composition method development will require extending the boundaries of the field as it now exists.
机译:审查的目的:一百多年来的研究导致了在原子,分子,细胞和组织系统水平上测量所有主要人体成分的方法。这些非凡的发展推动了“人体成分”生物学研究结果和相关出版物的持续快速增长。除了对现有方法进行细微,逐步的改进外,是否不再需要开发新的身体成分方法了?这篇评论探讨了一个问题:我们是否正在接近人体成分方法学研究的“终点”?最新发现:“传统”人体成分研究之外的新兴且快速增长的领域突显了对开发新的创新方法的需求。最近引入的技术(例如正电子发射断层扫描和功能磁共振成像)将“质量”估计扩展到人体中相应的“功能”和生理学。尽管现在可以测量人体中的所有主要成分,但是在考虑诸如辐射暴露,侵袭性,静态与动态测量以及实验室与临床和现场评估等因素时,仍然存在很大差距。简介:人体组成方法开发第一阶段的结束现已到来:所有主要成分均可在体内测量。这些方法的可及性正在刺激从子宫内到老年的围绕人体成分的生物学知识的迅速发展。要在新的人体成分方法开发方面取得持续进展,就需要扩大该领域的界限,因为它已经存在。

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