Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma

Ribas Antoni; Hamid Omid; Daud Adil; Hodi F. Stephen; Wolchok Jedd D.; Kefford Richard; Joshua Anthony M.; Patnaik Amita; Hwu Wen-Jen; Weber Jeffrey S.; Gangadhar Tara C.; Hersey Peter; Dronca Roxana; Joseph Richard W.; Zarour Hassane; Chmielowski Bartosz; Lawrence Donald P.; Algazi Alain; Rizvi Naiyer A.; Hoffner Brianna; Mateus Christine; Gergich Kevin; Lindia Jill A.; Giannotti Maxine; Li Xiaoyun Nicole; Ebbinghaus Scot; Kang S. Peter; Robert Caroline

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Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma

机译：派姆单抗与晚期黑色素瘤患者肿瘤反应和生存率的关系

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IMPORTANCE The programmed death 1 (PD-1) pathway limits immune responses to melanoma and can be blocked with the humanized anti-PD-1 monoclonal antibody pembrolizumab.

机译：重要性程序性死亡1（PD-1）途径限制了对黑素瘤的免疫反应，可以被人源化抗PD-1单克隆抗体pembrolizumab阻断。

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《JAMA: the Journal of the American Medical Association》 |2016年第15期|共10页
作者
Ribas Antoni; Hamid Omid; Daud Adil; Hodi F. Stephen; Wolchok Jedd D.; Kefford Richard; Joshua Anthony M.; Patnaik Amita; Hwu Wen-Jen; Weber Jeffrey S.; Gangadhar Tara C.; Hersey Peter; Dronca Roxana; Joseph Richard W.; Zarour Hassane; Chmielowski Bartosz; Lawrence Donald P.; Algazi Alain; Rizvi Naiyer A.; Hoffner Brianna; Mateus Christine; Gergich Kevin; Lindia Jill A.; Giannotti Maxine; Li Xiaoyun Nicole; Ebbinghaus Scot; Kang S. Peter; Robert Caroline;
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1. Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma [J] . Ribas Antoni, Hamid Omid, Daud Adil, JAMA: the Journal of the American Medical Association . 2016,第15期

机译：派姆单抗与晚期黑色素瘤患者肿瘤反应和生存率的关系
2. Association of Vitiligo With Tumor Response in Patients With Metastatic Melanoma Treated With Pembrolizumab [J] . Hua Camille, Boussemart Lise, Mateus Christine, JAMA dermatology . 2016,第1期

机译：派姆单抗治疗转移性黑色素瘤患者白癜风与肿瘤反应的关系
3. B7-h4 expression in human melanoma: its association with patients' survival and antitumor immune response. [J] . Quandt D, Fiedler E, Boettcher D, Clinical cancer research: an official journal of the American Association for Cancer Research . 2011,第10期

机译：B7-h4在人黑素瘤中的表达：与患者的生存和抗肿瘤免疫反应有关。
4. PROTEOMIC PROFILING OF MELANOMA CELL LINES AND TISSUE USING DATA INDEPENDENT ACQUISITION MASS SPECTROMETRY TO PREDICT TREATMENT RESPONSE AND PATIENT SURVIVAL [C] . Christoph Krisp, Robert Parker, Dana Pascovici, International Mass Spectrometry Conference . 2018

机译：黑色素瘤细胞系和组织的蛋白质组学分析使用数据无关的采集质谱来预测治疗反应和患者存活
5. Associating Computed Tomography (CT) Imaging Response Criteria and Texture Analysis Measurements with Survival in Patients with Metastatic Melanoma Treated with Anti-angiogenic Therapy. [D] . Gray, Mark Russell. 2014

机译：将计算机断层扫描（CT）成像反应标准和纹理分析测量值与接受抗血管生成治疗的转移性黑色素瘤患者的生存率相关联。
6. Patterns of response in patients with advanced melanoma treated with Pembrolizumab (MK-3475) and evaluation of immune-related response criteria (irRC) [O] . F Stephen Hodi, Antoni Ribas, Adil Daud, 2014

机译：派姆单抗（MK-3475）治疗的晚期黑色素瘤患者的反应模式和免疫相关反应标准（irRC）的评估
7. Association of pembrolizumab with tumor response and survival among patients with advanced melanoma [O] . Ribas, Antoni, Hamid, Omid, Gangadhar, Tara C., 2016

机译：pembrolizumab与晚期黑色素瘤患者肿瘤反应和生存的关系

Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma

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