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首页> 外文期刊>JAMA: the Journal of the American Medical Association >Providing price displays for physicians which price is right?
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Providing price displays for physicians which price is right?

机译:为医生提供价格显示,哪个价格合适?

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The Human Genome Project not only provided the essential reference map for the human genome but also stimulated the development of technology and analytic tools to process massive quantities of genomic data. As a result of this project, new technologies for DNA sequencing have improved in efficiency and cost by more than a millionfold over the past decade, and these technologies can now be routinely applied at a cost of less than $5,000 per genome. Although the application of these technologies in cancer genomics research has continued to contribute to basic discoveries, opportunities for translating them for individual patients have also emerged. This is especially important in clinical cancer research, where genetic alterations in a patient's tumor may be matched to molecularly targeted therapies. In this review, we discuss the integration of cancer genomics and clinical oncology and the opportunity to deliver precision cancer medicine.
机译:人类基因组计划不仅为人类基因组提供了必要的参考图谱,而且刺激了处理大量基因组数据的技术和分析工具的发展。这个项目的结果是,过去十年来DNA测序的新技术的效率和成本提高了100万倍以上,现在可以常规应用这些技术,每个基因组的成本不到5,000美元。尽管这些技术在癌症基因组学研究中的应用继续为基础发现做出了贡献,但也为个体患者提供了将其翻译的机会。这在临床癌症研究中尤其重要,在该研究中,患者肿瘤的遗传改变可能与分子靶向疗法相匹配。在这篇综述中,我们讨论了癌症基因组学与临床肿瘤学的整合以及提供精确的癌症医学的机会。

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