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Contralateral prophylactic mastectomy for breast cancer addressing peace of mind

机译:对侧预防性乳腺癌乳房切除术可让您安心

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Addressing patients' fears and concerns about the effects of disease and its treatments on their lives and on their families is an important goal of cancer management. This is challenging for clinicians because these issues are complicated and difficult to explore in brief visits. A diagnosis of breast cancer and the sudden escalation of decisions trigger powerful emotional reactions from patients. Patients generally feel well at the time of diagnosis but suddenly confront a major health threat, a complicated decision context, and an arduous treatment course. Virtually all treatments that confer lifetime benefit are initiated in the first few months after diagnosis, and the decision-making process is generally compressed into the first few weeks. A sense of urgency in treatment planning is reinforced by the experiences of family and friends, by the powerful messages in the media, and by some clinicians who advise patients to initiate treatment quickly. The increasing use of the time from an abnormal mammogram to definitive cancer surgery as a quality measure in some systems further reinforces the impression that any delay may result in a worsening of prognosis. Consequently, it is understandable that many patients want to do prophylactic mastectomy for patients with unilateral breast cancer has increased markedly in recent years and is much more frequently performed than bilateral prophylactic mastectomy for women without a diagnosis of breast cancer. In a study using the National Inpatient Sample, the rate of CPM for unilateral breast cancer increased from 39 to 207 per 1000 mastectomies between 1998 and 2008, representing about 20 000 patients in 2008. In contrast, the rate of bilateral prophylactic mastectomy increased from 5 to 18 per 1000 mastectomies during the same period.
机译:解决患者对疾病及其治疗方法对其生活和家庭的影响的担忧和担忧是癌症治疗的重要目标。对于临床医生而言,这是一个挑战,因为这些问题很复杂,并且很难在短时间内探查。乳腺癌的诊断和决策的突然升级会触发患者强烈的情绪反应。患者通常在诊断时感觉良好,但突然面临主要的健康威胁,复杂的决策环境和艰巨的治疗过程。实际上,所有可终身受益的治疗方法都是在诊断后的头几个月开始,通常将决策过程压缩到头几周。家人和朋友的经历,媒体上强有力的信息以及一些建议患者迅速开始治疗的临床医生会增强治疗计划中的紧迫感。在某些系统中,越来越多地使用从异常的乳房X线检查到确定的癌症手术的时间作为一种质量指标,这进一步增强了这样的印象,即任何延迟都可能导致预后恶化。因此,可以理解的是,近年来许多患者希望对单侧乳腺癌患者进行预防性乳房切除术,而对于没有诊断为乳腺癌的女性,与双侧预防性乳房切除术相比,执行这种术的频率要高得多。在一项使用“全国住院患者样本”的研究中,单侧乳腺癌的CPM比率从1998年至2008年从每1000例切除术中的39例增加到207例,2008年约有20000例患者。相反,双侧预防性乳房切除术的比率从5例增加到同一时期每1000个乳房切除术增加18个。

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