Direct evidence of a blocking heavy atom effect on the water-assisted fluorescence enhancement detection of Hg~(2+) based on a ratiometric chemosensor?

摘要

At the current stage of chemosensor chemistry, the critical question now is whether the heavy atom effect caused by HTM ions can be blocked or avoided. In the present work, we provide unequivocal evidence to confirm that the heavy atom effect of Hg~(2+) is inhibited by water and other solvent molecules based on results using the chemosensor L. Most importantly, the heavy atom effect and blocking thereof were monitored within the same system by the use of ratiometric fluorescence signal changes of the pyrene motif. These observations not only serve as the foundation for the design of new ‘turnon’ chemosensors for HTM ions, but also open up new opportunities for the monitoring of organic reactions.