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首页> 外文期刊>Transplantation: Official Journal of the Transplantation Society >Spontaneous Splenorenal Shunt in Liver Transplantation: Results of Left Renal Vein Ligation Versus Renoportal Anastomosis
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Spontaneous Splenorenal Shunt in Liver Transplantation: Results of Left Renal Vein Ligation Versus Renoportal Anastomosis

机译:肝移植中的自发性脾肾分流:左肾静脉结扎与肾门静脉吻合术的结果

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摘要

Background. Management of portal inflow to the graft in patients with spontaneous splenorenal shunts (SRS) is a matter of concern especially in case of large varices (more than 1 cm). In case of portal vein (PV) thrombosis (PVT), renoportal anastomosis (RPA) directly diverts the splanchnic and renal venous blood assuring a good portal inflow to the graft. Disconnection of the portacaval shunt by left renal vein ligation (LRVL) is another option but requires a patent PV. The indication of primary RPA rather than LRVL in patients with small native PV, especially in case of large graft, should be questioned in these complex cases of liver transplantation. Methods. From 1998 to 2012, 17 patients with RPA and 15 patients with LRVL were transplanted in our center. We compared these 2 techniques for short-and long-term results. Results. The rate of preliver transplantation PVT (76% vs 27%) and graft weight (1538 +/- 383 g vs 1293 +/- 216 g) was significantly higher in the RPA group. Renoportal anastomosis was performed in 4 cases of small but patent PV. Three-month mortality, morbidity, and massive ascitis were similar. No patient was retransplanted. One year after transplantation, PV diameter was still larger in RPA group. Three-year survival was similar (RPA: 79% vs LRVL: 53%, P = 0.1). Conclusions. In cirrhotic patients transplanted with large splenorenal shunts, RPA and LRVL reach similar survivals. In case of complete PVT and failure of thrombectomy, the RPA offers satisfactory long-term results.
机译:背景。自发性脾肾分流术(SRS)患者的门静脉流入管理是一个值得关注的问题,尤其是在大静脉曲张(大于1 cm)的情况下。如果发生门静脉(PV)血栓形成(PVT),则肾门静脉吻合术(RPA)直接转移内脏和肾脏静脉血,确保良好的门静脉流入移植物。通过左肾静脉结扎术(LRVL)断开门腔分流术是另一种选择,但需要获得专利PV。在这些复杂的肝移植病例中,对于天然小PV的患者,尤其是大移植物的患者,主要RPA而不是LRVL的适应症应受到质疑。方法。从1998年到2012年,我们中心移植了17例RPA患者和15例LRVL患者。我们比较了这两种技术的短期和长期结果。结果。 RPA组的肝移植PVT率(76%比27%)和移植物重量(1538 +/- 383 g对1293 +/- 216 g)显着更高。肾小管吻合术在4例小但未闭的PV中进行。三个月的死亡率,发病率和大规模腹水相似。没有患者被移植。移植一年后,RPA组的PV直径仍较大。三年生存率相似(RPA:79%vs LRVL:53%,P = 0.1)。结论。在移植有大型脾肾分流器的肝硬化患者中,RPA和LRVL的存活率相似。如果发生完全的PVT且血栓切除失败,则RPA可提供令人满意的长期结果。

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