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Evaluation of Immune Profiles and MicroRNA Expression Profiles in Peripheral Blood Mononuclear Cells of Long-Term Stable Liver Transplant Recipients and Recipients With Acute Rejection Episodes

机译:长期稳定的肝移植受者和急性排斥发作的受者外周血单个核细胞的免疫特征和microRNA表达特征的评估

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摘要

Objective. This study aimed to document the difference of immunophenotypes in peripheral blood mononuclear cells (PBMCs) between long-term stable liver transplant recipients and recipients with acute rejection. We also sought to identify whether there is any correlation between microRNA (miRNA) expression profile and the differential immunoprofile in these 2 groups to establish a specific miRNA biomarker to identify potential liver transplant recipients.
机译:目的。这项研究旨在证明长期稳定的肝移植受者与急性排斥反应的受者之间外周血单核细胞(PBMC)免疫表型的差异。我们还试图确定这两个组中的microRNA(miRNA)表达谱和差异免疫谱之间是否存在任何相关性,以建立特定的miRNA生物标记物以鉴定潜在的肝移植受者。

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