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A comparison of open surgery and endovascular intervention for hepatic artery complications after pediatric liver transplantation

机译:小儿肝移植后开放手术与腔内介入治疗肝动脉并发症的比较

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There are currently 2 major therapeutic options for the treatment of hepatic artery complications: endovascular intervention and open surgery. We herein report a retrospective analysis of 14 pediatric patients with hepatic artery complications after pediatric living donor liver transplantation (LDLT) at our institution. We divided them into an open surgery group and an endovascular intervention group based on their primary treatment, and compared the results and outcomes. We then evaluated which procedure is more effective and less invasive. In the open surgery group, recurrent stenosis or spasm of the hepatic artery occurred in 3 of the 8 patients (37.5%). In the endovascular intervention group, 5 of the 6 patients were technically successfully treated by only endovascular treatment. Of the 5 successfully treated patients, 3 developed recurrent stenosis (60%). There were significant differences in the mean length of the operation for the first treatment of hepatic artery complications (open surgery, 428 minutes vs endovascular intervention, 160 minutes; P =.01) and in the mean value of the posttreatment aspartate aminotransferase (AST)/alanine aminotransferase (ALT) (open surgery > endovascular intervention; P =.04/.05). Although endovascular intervention needs to be examined in further studies to reduce the rate of relapse, it is a less invasive method for the patient and graft than open surgery. ? 2013 Elsevier Inc.
机译:当前有两种主要的治疗肝动脉并发症的治疗方法:血管内介入和开放手术。我们在这里报告了在我们机构对14例小儿活体供体肝移植(LDLT)后发生肝动脉并发症的小儿患者的回顾性分析。根据他们的主要治疗方法,我们将他们分为开放手术组和血管内干预组,并比较结果和结果。然后,我们评估了哪种方法更有效且侵入性更小。在开放手术组中,8例患者中有3例发生了肝动脉反复狭窄或痉挛(37.5%)。在血管内干预组中,仅通过血管内治疗在技术上成功地治疗了6例患者中的5例。在5例成功治疗的患者中,有3例复发性狭窄(60%)。首次治疗肝动脉并发症的平均手术时间(开放手术,428分钟vs血管内介入治疗,160分钟; P = .01)和治疗后天冬氨酸转氨酶(AST)的平均值存在显着差异。 /丙氨酸氨基转移酶(ALT)(开放手术>血管内干预; P = .04 / .05)。尽管需要在进一步的研究中检查血管内干预以降低复发率,但与开放手术相比,它对患者和移植物的侵入性较小。 ? 2013爱思唯尔公司

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