Advise about perampanels effect on contraceptives choice

摘要

PHARMACISTS should ensure that women with epilepsy who are prescribed higher doses of perampanel (Fycompa) are aware of the drug's impact on progestogen-containing contraceptives and are given appropriate advice, according to the Drug and Therapeutics Bulletin. May's DTB Select highlights recent advice from the Faculty of Sexual and Reproductive Healthcare's clinical effectiveness unit, which states that the efficacy of oral contraceptives, transdermal patches, vaginal rings and progesto-gen-only implants may be reduced by enzyme inducers such as perampanel.