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Developing biomaterials for tissue engineering and regenerative medicine

机译:开发用于组织工程和再生医学的生物材料

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DAMAGED and degenerated tissues resulting from disease, trauma or injury need treatment to facilitate their repair, replacement or regeneration. Traditionally treatment for damaged tissues has focused on transplantation of tissue from one area of individual to another (autograft), or from one individual to another person (a transplant or allograft). Despite the fact that these are life-saving and revolutionary techniques, each is associated with major problems. Harvesting autografts is an expensive, painful procedure constrained by anatomical limitations and can result in infection and haematoma. The use of allografts and transplants is limited due to issues with accessing enough tissues for all patients and the risk of rejection by the host patient's immune system. Risk of infection or disease being contracted by the patient from the donor is also a consideration.
机译:因疾病,外伤或受伤而造成的受损和退化的组织需要进行治疗,以促进其修复,替换或再生。传统上,对受损组织的治疗集中在将组织从一个人的区域移植到另一个区域(自体移植),或从一个人到另一个人(移植或同种异体移植)。尽管这些都是拯救生命的革命性技术,但每种技术都存在重大问题。自体移植物的收获是昂贵的,痛苦的过程,受到解剖学限制,并可能导致感染和血肿。同种异体移植物和移植物的使用受到限制,这是因为所有患者都需要接触足够的组织,并且存在宿主患者免疫系统排斥的风险。还考虑患者从供体感染感染或疾病的风险。

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