One of the earliest attempts to reach international agreement on preventing the use of poison or poisoned weapons took place at the Brussels Convention of 1874. Later, at the Hague Conference in 1899, the participating states pledged "not to employ asphyxiating or deleterious gases". In 1928, following the horrors of the 1914-18 war, the Geneva Protocol set out to prohibit the use of "asphyxiating, poisonous or other gases and of bacteriological methods of warfare" but it did not mention developing or stockpiling them.
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