Partial breast irradiation: new standard for selected patients.

摘要

Routine whole-breast radiotherapy comprises 50 Gy in daily fractions for 5 weeks. The additional application of an external boost of 10-16 Gy to the tumour bed leads to excellent local tumour control, with local recurrence rates around 6% after a median of 10-years follow-up. However, in view of the low and focal local recurrence rates, the concept of accelerated partial-breast irradiation has gained widespread interest with various methods.