Radiotherapy in locally advanced prostate cancer.

摘要

Long-term hormonal therapy has long been regarded as the mainstay of treatment for men with locally advanced prostate cancer. Four key randomised controlled trials have shown that early use of hormonal therapy leads to improved overall survival. There has been no consensus about whether or not radical local treatment should be used in addition to hormonal therapy, and SPCG-7/SFUO-3,reported in The Lancet today, is the first randomised trial to address this issue.