Indazolium halides as efficient ligands for Pd-catalyzed Suzuki-Miyaura cross-coupling of aryl bromides with arylboronic acids

摘要

The indazolium halides containing various N-substituents have been conveniently prepared and applied in the palladium-catalyzed Suzuki-Miyaura cross-coupling reactions of aryl bromides with arylboronic acids at mild reaction conditions. The cross-coupling reaction provides the desired products in good to high yields. The ease of synthesis and the modularity, and the broad range of aryl bromides and arylboronic acids make this type of ligand attractive and promising for transition metal catalysis. (C) 2016 Elsevier Ltd. All rights reserved.