Arylation of allylphosphonates and application to the preparation of phosphonomethyl-coumarin, -quinolinone and -benzoxepinone skeletons

摘要

An efficient and selective synthesis of Z-(het)arylallylphosphonates is described. The versatile Pd-assisted process also allowed polyarylation sequences leading to star-shaped and binaphthyl derivatives. The methodology could be extended to the preparation of new phosphonomethyl-coumarin, -quinolinone, and -benzoxepinone architectures in high yields. (C) 2015 Elsevier Ltd. All rights reserved.