A catalyst-free N-H insertion/Mannich-type reaction cascade of α-nitrodiazoesters

摘要

A catalyst-free N-H insertion/Mannich-type reaction cascade of α-nitrodiazoesters with anilines has been developed to afford a variety of α-amino-α-aryl esters in 60-83% yields and under mild reaction conditions (23 or 40 °C).