Pyrrolidine-diaminomethylenemalononitrile organocatalyst for Michael additions of carbonyl compounds to nitroalkenes under solvent-free conditions

摘要

The novel pyrrolidine-diaminomethylenemalononitrile organocatalyst 7 promotes the asymmetric conjugate addition of a carbonyl compound to a nitroalkene to afford the corresponding adduct in high yield with up to 99% ee, under solvent-free conditions.