Reactivity of trihexyl(tetradecyl)phosphonium chloride,a room-temperature phosphonium ionic liquid

摘要

Trihexyl(tetradecyl)phosphonium chloride 1,a room-temperature ionic liquid,readily undergoes deuterium isotope exchange reaction in deuterated solvents.Under basic conditions,ionic liquid 1 was reactive and 50% deuterium exchanged on all four P-CH2 methylene groups in 9 h at ambient temperature,30 min at 50 °C,or 12 min at 65 °C.In addition,ionic liquid 1 reacted with sodium salts of substituted benzoates apparently through the direct SN2 carboxylate alkylation to form esters 2 and the resulting esters further converted,via Wittig reaction,to finally afford aryl ketones 4.