Studies on organophosphorus compounds: reactions of benzosuberones with 2,4-bis(p-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-disulfide (Lawesson's reagent)

摘要

6-Arylidene-3-methyl-6,7,8,9-tetrahydro-5H-benzo[a]cyclohepten-5-ones (2a–h), obtained by the condensation of 3-methylbenzocyclohepten-5-one 1 with appropriate aromatic aldehydes, on reaction with Lawesson's reagent in xylene yielded phosphorus containing compounds 3a–h. A number of these compounds showed promising anti-inflammatory activity.