Efficient synthesis of trisubsttuted alkenes in an aqueous-organic system using a versatile and recyclable Rh/m-TPPTC catalyst

摘要

We have found that the use of [Rh(cod)OH]_2 associated iwht thewater-soluble ligand m-TPPTC washighly efficient for the Rh-catalyzed arylation of alkynes.aryl and alkyl alkynes were transformed to alkenes using 3 mol% rhodium catalyst and 2.5 equiv of boronic acid at 100 deg C in abiphasic water/toluene system in 80-99% yield.The reacton was foudn to be totally regio-selective for alkyl arylalkynes and alkyl silylated alkyns.The Rh/m-TPPTC system was for the frist time recycled with no loss of the activit and with excellent purity of the desired alkene.