Bacillamide, a novel algicide from the marine bacterium, Bacillus sp. SY-1, against the harmful dinoflagellate, Cochlodinium polykrikoides

摘要

Bacillamide (1) was isolated as a new algicide against the harmful dinoflagellate, Cochlodinium polykrikoides, from the marine bacterium, Bacillus sp. SY-1, and its structure was elucidated by extensive two-dimensional NMR techniques including ~1H-~(15)N HMBC analysis and mass analysis. Bacillamide showed algicidal activity against C. polykrikoides with LC_(50) of 3.2 μg/ml.