A novel fluorescence turn-on coumarin-pyrazolone based monomethine probe for biothiol detection

Babur Banu; Seferoglu Nurgul; Ocal Muge; Sonugur Gizem; Akbulut Hakan; Seferoglu Zeynel

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A novel fluorescence turn-on coumarin-pyrazolone based monomethine probe for biothiol detection

机译：一种新型的基于荧光素的香豆素-吡唑啉酮单甲胺荧光探针用于生物硫醇检测

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摘要

A coumarin-pyrazolone monomethine based turn-on fluorescence ratiometric probe C-3 for selective detection of cysteine (Cys) and glutathione (GSH) is reported. It exhibits OFF-ON states and is more sensitive to GSH in aqueous solution neutral and basic pH. The ON state is due to the inhibition of intramolecular charge transfer (ICT) process between pyrrole and pyrazolone moieties. (C) 2016 Elsevier Ltd. All rights reserved.

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《Tetrahedron》 |2016年第30期|共5页
作者
Babur Banu; Seferoglu Nurgul; Ocal Muge; Sonugur Gizem; Akbulut Hakan; Seferoglu Zeynel;
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正文语种 eng
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Coumarin-pyrazolone hybrid; Fluorescence turn-on probe; Biothiols detection; Michael acceptor; ICT inhibition; DFT calculations;

机译：香豆素-吡唑啉酮杂种;荧光开启探针;生物硫醇检测;迈克尔受体;ICT抑制;DFT计算;

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专利

1. A novel fluorescence turn-on coumarin-pyrazolone based monomethine probe for biothiol detection [J] . Babur Banu, Seferoglu Nurgul, Ocal Muge, Tetrahedron . 2016,第30期

机译：一种新型的基于荧光素的香豆素-吡唑啉酮单甲胺荧光探针用于生物硫醇检测
2. A selective fluorescence probe for H_2S from biothiols with a significant regioselective turn-on response and its application for H_2S detection in living cells and in living Caenorhabditis elegans [J] . Yang Bing, Su Mi-Mi, Xue Yun-Sheng, Sensors and Actuators . 2018,第DECa期

机译：具有明显区域选择性开启反应的生物硫醇中H_2S的选择性荧光探针及其在活细胞和秀丽隐杆线虫中检测H_2S的应用
3. A novel nitroethylene-based porphyrin as a NIR fluorescence turn-on probe for biothiols based on the Michael addition reaction [J] . Wang Qing, Ma Fangtao, Tang Weiqiang, Dyes and Pigments . 2018,第期

机译：基于迈克尔加成反应的生物醇的新型硝基丙烯基卟啉作为生物醇的NIR荧光开启探针
4. Development of a Novel Fiber Optic Sensor Combined with a Fluorescence Turn-on Probe for Cu (II) Detection [C] . J. Ma, Y. Chiniforooshan, W. H. Hao, International Conference on Heavy Metals in the Environment . 2014

机译：新型光纤传感器的开发结合Cu（II）检测的荧光开启探针
5. Development of multi-probe fluorescence-based assay for bonta detection. [D] . Dadgar, Saedeh. 2014

机译：用于探针检测的基于多探针荧光的检测方法的开发。
6. A 7-Hydroxybenzoxazinone-Containing Fluorescence Turn-On Probe for Biothiols and Its Bioimaging Applications [O] . Bin Li, Datong Zhang, Ruibing An, 2019

机译：含7-羟基苯并恶嗪酮的生物硫醇荧光开启探针及其生物成像应用
7. A new fluorescence turn-on probe for biothiols based on photoinduced electron transfer and its application in living cells [O] . Jianxi Wang, Cheng Zhou, Jianjian Zhang, 2016

机译：基于光导电子转移的生物硫醇新的荧光开启探针及其在活细胞中的应用

A novel fluorescence turn-on coumarin-pyrazolone based monomethine probe for biothiol detection

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