Application of in vivo laser scanning confocal microscopy for evaluation of ocular surface diseases: Lessons learned from pterygium, meibomian gland disease, and chemical burns

摘要

In our previous study,2 we evaluated goblet cell density on bulbar conjunctiva and cornea in patients with ocular chemical burns by in vivo LSCM and impression cytology. A significant positive correlation was found between the goblet cell densities using these 2 methods. However, the confocal study of goblet cells (GCs) by Villani et al3 found that it was difficult to differentiate, quantify, and interpret the GCs. It seems that the 2 studies were not consistent. Villani et al3 examined the lower tarsal conjunctiva in their study, whereas we checked the bulbar conjunctiva in our study.