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Oxygen transmissibility of piggyback systems with conventional soft and silicone hydrogel contact lenses.

机译:采用传统的软性和有机硅水凝胶隐形眼镜,搭载系统的氧气透过率。

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PURPOSE: To investigate the apparent oxygen transmissibility of various piggyback systems using conventional and silicone hydrogel soft contact lenses of different water content and permeability, rigid poly(methyl methacrylate), and rigid gas-permeable lenses of medium, high, and ultrahigh oxygen permeability. The aim of the study was to establish which material (rigid or hydrogel) is more representative of the resulting oxygen performance of piggyback systems. METHODS: The apparent oxygen transmissibility of 66 piggyback systems was measured with an electrochemical method. Eighteen of these combinations involved the use of silicone hydrogel contact lenses currently available. One hyperpermeable rigid gas-permeable contact lens (tisilfocon A) was also included in the study. RESULTS: Measured apparent transmissibility correlates with rigid lens permeability (r = 0.403; SE = +/-3.03 barrer/cm; P < 0.001) and hydrogel lens permeability (r = 0.334; SE = +/-3.2 barrer/cm; P < 0.001). As expected, a linear model comprising permeability values from both rigid and soft materials gave a more precise estimation of the piggyback transmissibility (r = 0.736; SE = +/-2.02 barrer/cm; P < 0.001). The highest values of apparent oxygen transmissibility were found for the combination of tisilfocon A rigid material with any of the 3 silicone hydrogel lenses. Tisilfocon A material significantly improved the transmissibility of all piggyback systems even when conventional hydrogels are involved. CONCLUSION: The combination of hypertransmissible rigid gas permeable lenses with silicone hydrogel soft materials should result in normal corneal function under daily wear conditions. When fitting piggyback systems, clinicians must be aware of material selection to optimize oxygen performance. This is of particular importance in already compromised corneas.
机译:目的:研究使用不同水含量和渗透率的常规和有机硅水凝胶软质隐形眼镜,硬质聚甲基丙烯酸甲酯和中,高和超高透氧性的硬质透气性镜片,对各种搭载系统的表观氧气透过率。该研究的目的是确定哪种材料(刚性或水凝胶)更能代表搭载系统的氧气性能。方法:采用电化学方法测量了66个背负式系统的表观氧气透过率。这些组合中有18种涉及使用当前可用的有机硅水凝胶隐形眼镜。该研究还包括一种高透性硬质透气隐形眼镜(tisilfocon A)。结果:测得的表观透射率与刚性镜片的渗透性(r = 0.403; SE = +/- 3.03 barrer / cm; P <0.001)和水凝胶镜片的渗透性(r = 0.334; SE = +/- 3.2 barrer / cm; P <相关0.001)。如预期的那样,包含来自硬质材料和软质材料的渗透率值的线性模型可以更精确地估算背负式传输率(r = 0.736; SE = +/- 2.02 barrer / cm; P <0.001)。 tisilfocon A刚性材料与3种有机硅水凝胶镜片中的任何一种的组合,发现最高的表观氧气透过率。 Tisilfocon A材料可显着改善所有背负系统的透射率,即使使用常规水凝胶也是如此。结论:高透性硬质透气性镜片与有机硅水凝胶软质材料的结合在日常佩戴条件下应能使角膜功能正常。在安装背负式系统时,临床医生必须注意选择材料以优化氧气性能。这在已经受损的角膜中尤其重要。

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