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Immediate postpartum etonogestrel implant: A contraception option with long-term continuation

机译:产后立即服用依托孕酮:长期持续使用的避孕方法

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Objective: To determine 3-year continuation rates of the etonogestrel contraceptive implant when inserted immediately postpartum and to identify factors associated with discontinuation. Study Design: A retrospective cohort of 262 women who had the contraceptive implant inserted immediately postpartum between January 2008 and March 2009 was collected from electronic medical records. Continuation rates at 1, 2 and 3 years were estimated. Adverse effects leading to removal of the implant were recorded. Multivariable Cox proportional hazard models were performed to determine factors associated with early discontinuation. Results: Large subsets of the study patients were adolescent (28.2%) and multigravid (71.8%) and presented for fewer than six prenatal visits (38.5%). Follow-up rates were over 70% at each of the 3 years. Adolescents and women with fewer than six prenatal visits had the highest continuation rates at 1 year, 94.5% and 94.1%, respectively. The cumulative implant continuation rate after 3 years was 66.3%. Multivariable analysis indicated that having six or more prenatal care visits was the only independent predictor of early discontinuation, with a hazard ratio of 3.1 (p=0.04) and 1.8 (p=<0.01) at 1 and 3 years, respectively. The most commonly reported reasons for early removal were abnormal bleeding (41.2%) and weight gain (19.1%). Conclusion: The contraceptive implant has high continuation over its 3-year lifespan when inserted immediately postpartum. Continuation rates were highest among populations most vulnerable to rapid repeat and unintended pregnancies. Implications: The etonogestrel implant, when placed immediately postpartum for contraception, can have high continuation rates of use for up to 3 years duration.
机译:目的:确定产后立即插入依托孕酮避孕植入物的3年持续率,并确定与停药有关的因素。研究设计:回顾性研究了从电子病历中收集的262名在2008年1月至2009年3月之间立即产后植入避孕植入物的女性的研究结果。估计在1、2和3年的延续率。记录了导致去除植入物的不利影响。进行多变量Cox比例风险模型以确定与早期停药相关的因素。结果:研究患者的大部分亚组为青春期(28.2%)和多重性(71.8%),并进行了少于6次产前检查(38.5%)。在这三年中,每年的随访率均超过70%。少于六次产前检查的青少年和妇女在1年时的最高延续率分别为94.5%和94.1%。 3年后的累积植入物持续率为66.3%。多变量分析表明,进行六次或更多次产前检查是早期中止的唯一独立预测因素,在1年和3年时的危险比分别为3.1(p = 0.04)和1.8(p = <0.01)。据报道,提早取出的最常见原因是异常出血(41.2%)和体重增加(19.1%)。结论:产后立即插入避孕植入物,在其3年寿命中具有较高的延续性。在最容易发生快速重复和意外怀孕的人群中,继续感染率最高。含义:产后立即将依托孕酮植入物用于避孕,在长达3年的持续使用中具有很高的持续使用率。

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