High-resolution NMR spectroscopy via simultaneous acquisitions of intermolecular zero- and double-quantum coherence signals in inhomogeneous magnetic fields

摘要

High-resolution nuclear magnetic resonance spectroscopy is widely used to analyze molecular structures and compositions. Here, we present a pulse sequence that simultaneously detects both intermolecular zero- (iZQC) and double-quantum coherence (iDQC) signals in inhomogeneous fields, offering high-resolution spectra in absolute-value mode after data processing. In comparison with pure iZQC or iDQC spectra, the proposed sequence can provide nearly doubled spectral resolutions and suppressions of strong coupling artifacts. It is the first time that iZQC and iDQC signals can be simultaneously obtained in one single measurement. This sequence may provide an alternative approach to studies of in situ inhomogeneous chemical systems. (C) 2015 Elsevier B.V. All rights reserved.