Nitronyl Nitroxide as a Coupling Partner: Pd-Mediated Cross-coupling of (Nitronyl nitroxide-2-ido)(triphenylphosphine)gold(I) with Aryl Halides

摘要

A cross-coupling reaction using nitronyl nitroxide (NN) as a coupling partner was developed: Refluxing a mixture of [Au~I(NN-2-ido)(PPh3)] and aryl iodide (Ar-I) in THF in the presence of 10mol% [Pd(PPh3)4] produced a cross-coupling product NN-Ar in a high yield. This method allowed the direct introduction of the NN radical onto various poly-and heterocyclic aromatic rings.