Comparative Study of Aqueous Solutions of Cationic Surfactants: Structure/Activity Relation in Their Aggregation and Solubilization Behavior and Complexation with an Oligonucleotide

摘要

For mono- and dicationic surfactants with trimethylammo-nium (TMA), triphenylphosphonium (TPP), and 4-aza-1-alkyl-1-azoniabicyclo[2.2.2]octane (DABCO) polar groups, and also for pyrimidinic amphiphiles, a correlation is revealed between their aggregation and solubilization properties and their complexation capacity toward an oligonucleotide. Mixed cationic surfactant-calixarene systems demonstrate controllable binding/ release properties.