Microbiomarkers with big impact in CLL.

摘要

In this issue of Blood, Ferrajoli et al examined the microRNA (miRNA) miR-155 as a biomarker for chronic lymphocytic leukemia (CLL), Increased expression of cellular and plasma miR-155 was observed in patients with CLL and correlated with poor survival and therapeutic response, suggesting that plasma-based noncoding UNA biomarkers may one day be a reality.