Acrodermatitis enteropathica (AE) is a rare autosomal recessive inherited form of zinc deficiency caused by a mutation of the SLC39A4 gene, which encodes the zinc/iron-regu!ated, transporter-like protein, which is located on chromosome 8q24.3. AE presents during infancy with the classic clinical triad of acral dermatitis, alopecia, and diarrhea. The cutaneous manifestations of AE typically occur within 1 to 2 weeks upon weaning the child from breast milk; however this may vary based upon the etiology. Here is an atypical case of delayed onset AE in a 3-year-old Caucasian female.
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