A CMO's Approach: To Provide World-Class Cell Culture Development and Manufacturing Services

摘要

Industry leading biologies contract manufacturer Fujifilm Diosynth Biotechnologies located in Research Triangle Park, NIC (formerly Diosynth Biotechnology) and in Billingham, UK (formerly Avecia Biologies) provides third-party contract development andmanufacturing services to the biopharmaceutical industry. Fujifilm Diosynth Biotechnologies has supplied clinical and commercial recombinant proteins produced in cell culture for more than 14 years. We have extensive experience in microbial developmentand manufacturing and equal experience in the cell culture space. Our development experience includes over 30 cell culture processes, of which two-thirds were CHO derived, and over 20 monoclonal antibody programs. In addition, Fujifilm Diosynth has executed four baculovirus programs with scale-up to 1,500-L for the first time in the industry for human use. To date, Fujifilm Diosynth has produced over 100 cell culture GMP batches, primarily using CHO cell and baculovirus technologies and manufactures onecell culture commercial product.