Comparative study of the structure of some genetic probes used for typing of Yersinia pestis strains

摘要

A nucleotide sequence comon for genetic probes used for detection and investigation of Y. pestis strains MK, IS100, and HRSIII was identified on the basis of restriction, hybrization, and computer analysis. This region of chromosomal DNA is a part of low-molecular BX-probe we have developed. The results of genomic fingerprinting of Y. pestis strains by the BX-probe are promising as regards its future untilization for typing the strains isolated in various endemic areas.