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Bayesian analysis of multivariate nominal measures using multivariate multinomial probit models

机译:使用多元多项式概率模型对多元名义度量进行贝叶斯分析

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摘要

The multinomial probit model has emerged as a useful framework for modeling nominal categorical data, but extending such models to multivariate measures presents computational challenges. Following a Bayesian paradigm, we use a Markov chain Monte Carlo (MCMC) method to analyze multivariate nominal measures through multivariate multinomial probit models. As with a univariate version of the model, identification of model parameters requires restrictions on the covariance matrix of the latent variables that are introduced to define the probit specification. To sample the covariance matrix with restrictions within the MCMC procedure, we use a parameter-extended Metropolis–Hastings algorithm that incorporates artificial variance parameters to transform the problem into a set of simpler tasks including sampling an unrestricted covariance matrix. The parameter-extended algorithm also allows for flexible prior distributions on covariance matrices. The prior specification in the method described here generalizes earlier approaches to analyzing univariate nominal data, and the multivariate correlation structure in the method described here generalizes the autoregressive structure proposed in previous multiperiod multinomial probit models. Our methodology is illustrated through a simulated example and an application to a cancer-control study aiming to achieve early detection of breast cancer.
机译:多项式概率模型已经成为一种用于对名义分类数据进行建模的有用框架,但是将此类模型扩展到多元度量会带来计算挑战。遵循贝叶斯范式,我们使用马尔可夫链蒙特卡洛(MCMC)方法通过多元多项式概率模型分析多元名义度量。与模型的单变量版本一样,模型参数的标识需要限制引入潜在变量的协方差矩阵,以定义概率标准。为了在MCMC程序中限制条件下对协方差矩阵进行抽样,我们使用了参数扩展的Metropolis-Hastings算法,该算法结合了人工方差参数,将问题转化为一组更简单的任务,包括对无限制协方差矩阵进行抽样。参数扩展算法还允许在协方差矩阵上进行灵活的先验分布。在此描述的方法中的现有技术规范概括了分析单变量名义数据的较早方法,而在此描述的方法中的多元相关结构对在先前的多周期多项式概率模型中提出的自回归结构进行了概括。我们的方法通过一个模拟示例进行说明,并应用于旨在实现早期发现乳腺癌的癌症对照研究。

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