RAPD in glaucoma

摘要

Purpose: To assess the amount of structural (retinal nerve fiber layer (RNFL) thickness loss, macular thickness (MT) and volume (MV) measured by optical coherence tomography (OCT)) and functional (visual acuity (VA), visual field mean deviation (MD), brightness sensitivity, and red perception) loss required for a relative afferent pupillary defect (RAPD) to manifest in patients with glaucoma. Methods: This case-control study prospectively enrolled 50 glaucoma patients: 25 with RAPD and 25 without. The presence of an RAPD was determined and quantified using the "swinging flashlight test", with neutral density filters. A separate examiner, masked to the pupillary findings, assessed participants for brightness sense, red perception, VA, MD, RNFL thickness, MT and MV.