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A prospective randomized treatment study comparing three treatment options for chalazia: triamcinolone acetonide injections, incision and curettage and treatment with hot compresses

机译:一项前瞻性随机治疗研究,比较了对褐斑病的三种治疗选择:曲安奈德注射液,切口和刮除术以及热敷治疗

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摘要

We thank Brown et al. for their interest in our study. We would firstly like to point out that in our paper, we did acknowledge its limitations as a result of relying on patients' self-assessment and the reduced validity of a delayed pain survey.An uncomplicated chalazion is not a sight-threatening condition and under routine circumstances at our Eye Unit, patients are not followed up after treatment. Therefore, our rationale for following patients up with a telephone call was that clinical observation to ascertain whether 'absolute clearance' of chalazia had been achieved was not necessary, as long as patients themselves were satisfied that their chalazia had resolved.The results of our paper are consistent with current literature which suggests that steroid injections achieve a lower resolution rate than incision and curettage. However, our study did yield a higher overall resolution rate with steroid injections than shown in previous studies and a much lower need for a second steroid injection than previously recorded. We hypothesize that this unexpected outcome may be related to the fact that we asked all patients to apply 5 min of digital massage over the chalazion at least three times daily for 1 week following the injection.Whereas there are reported cases of globe perforation secondary to transcutaneous eyelid injections without the use of a lid clamp, the steroid injections in our study were administered transconjunctivally, therefore, this risk was minimized and the use of a lid clamp was not necessary.
机译:我们感谢布朗等。对他们对我们研究的兴趣。我们首先要指出的是,在我们的论文中,我们确实承认了它的局限性是由于依靠患者的自我评估以及延迟疼痛调查的有效性降低。在我们眼科的常规情况下,不对患者进行治疗后的随访。因此,我们对患者进行电话随访的理由是,只要患者自己对自己的癫痫病已经解决感到满意,就不需要进行临床观察来确定是否达到了癫痫病的``绝对清除''。与当前的文献一致,后者表明类固醇注射比切口和刮除术的分辨率更低。但是,我们的研究确实比以前的研究显示了类固醇注射的整体拆分率更高,并且比以前记录的第二次类固醇注射的需求要低得多。我们假设这种意外的结果可能与以下事实有关:我们要求所有患者在注射后1周内每天至少3次在chalazion上进行5分钟数字按摩,而据报道有继发于球囊穿孔的病例在不使用眼睑夹的情况下进行眼睑注射,我们研究中的类固醇注射是经结膜给药的,因此,将这种风险降到最低,并且不需要使用眼睑夹。

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