Characterization of protective immune response elicited by a trimeric envelope protein from an Indian clade C HIV-1 isolate in rhesus macaques

Menon Veena; Priya Rangasamy Sneha; Labranche Celia; Montefiori David; Mahalingam Sundarasamy; Kalyanaraman Vaniambadi S.; Pal Ranajit

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Characterization of protective immune response elicited by a trimeric envelope protein from an Indian clade C HIV-1 isolate in rhesus macaques

机译：恒河猴中印度进化枝C HIV-1分离物的三聚体包膜蛋白引起的保护性免疫应答的表征

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Background Recent preclinical studies have demonstrated the use of properly folded trimeric HIV-1 envelope proteins as immunogen for eliciting protecting immune response in macaques.

机译：背景技术最近的临床前研究表明，适当折叠的三聚体HIV-1包膜蛋白可作为免疫原用于在猕猴中引发保护性免疫反应。

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《Journal of medical primatology》 |2015年第5期|共11页
作者
Menon Veena; Priya Rangasamy Sneha; Labranche Celia; Montefiori David; Mahalingam Sundarasamy; Kalyanaraman Vaniambadi S.; Pal Ranajit;
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正文语种 eng
中图分类灵长目;
关键词
gp145; mucosal challenge; vaccine;

机译：gp145;粘膜刺激;疫苗;

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专利

1. CHARACTERIZATION OF PROTECTIVE IMMUNE RESPONSE ELICITED BY A TRIMERIC ENVELOPE PROTEIN FROM AN INDIAN CLADE C HIV-1 ISOLATE IN RHESUS MACAQUES [J] . Menon Veena, Rangaswamy Sneha Priya, Labranche Celia, Journal of medical primatology . 2015,第5期

机译：恒河猴猕猴印度C株HIV-1分离株三聚体蛋白引起的保护性免疫反应的表征
2. Vaginal delivery of the recombinant HIV-1 clade-C trimeric gp140 envelope protein CN54gp140 within novel rheologically structured vehicles elicits specific immune responses. [J] . Curran R. M., Donnelly L., Morrow R. J., Vaccine . 2009,第48期

机译：在新型流变结构载体中，重组HIV-1进化枝C三聚体gp140包膜蛋白CN54gp140的阴道递送引发了特异性的免疫反应。
3. Polyvalent DNA prime and envelope protein boost HIV-1 vaccine elicits humoral and cellular responses and controls plasma viremia in rhesus macaques following rectal challenge with an R5 SHIV isolate [J] . Pal R, Wang SX, Kalyanaraman VS, Journal of medical primatology . 2005,第5a6期

机译：多价DNA素和包络蛋白增强HIV-1疫苗引发幽默和细胞反应，并控制恒河猴中的血浆病毒血症在直肠攻击后r5 shiv隔离物
4. Structural Studies of Trimeric SIV and HIV-1 Envelope Glycoproteins Using Cryo-Electron Tomography [C] . T.A. White, A. Bartesaghi, M.J. Borgnia, Microscopy and microanalysis.;Microscopy and microanalysis. . 2010

机译：三聚体SIV和HIV-1包膜糖蛋白的结构研究
5. Characterization of viral envelopes and cytokine responses among rhesus macaques immunized with vesicular stomatitis virus-based simian immunodeficiency virus (SIV) vaccines and challenged with pathogenic SIV. [D] . Gambhira, Ratish. 2012

机译：基于水泡性口炎病毒的猿猴免疫缺陷病毒（SIV）疫苗免疫并受到病原性SIV攻击的恒河猴的病毒包膜和细胞因子应答的特征。
6. Vaginal delivery of the recombinant HIV-1 clade-C trimeric gp140 envelope protein CN54gp140 within novel rheologically structured vehicles elicits specific immune responses [O] . Rhonda M. Curran, Louise Donnelly, Ryan J. Morrow, -1

机译：在新型流变结构化载体中重组HIV-1进化枝C三聚体gp140包膜蛋白CN54gp140的阴道递送引发特异性免疫反应
7. Vaginal delivery of the recombinant HIV-1 clade-C trimeric gp140 envelope protein CN54gp140 within novel rheologically structured vehicles elicits specific immune responses [O] . Curran, Rhonda M., Donnelly, Louise, Morrow, Ryan J., 2009

机译：在新型流变结构化载体中，重组HIV-1进化枝C三聚体gp140包膜蛋白CN54gp140的阴道递送引发特异性免疫反应

Characterization of protective immune response elicited by a trimeric envelope protein from an Indian clade C HIV-1 isolate in rhesus macaques

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