Author response to letter from Snyder et al. regarding manuscript entitled 'Effect of renal impairment on the pharmacokinetics of the dipeptidyl peptidase-4 inhibitor, linagliptin' by Graefe-Mody et al.

摘要

We appreciate the constructive feedback from Drs Snyder, Polasek and Doogue on our manuscript entitled 'Effect of renal impairment on the pharmacokinetics of the dipeptidyl peptidase-4 inhibitor, linagliptin' [1] and thank you for providing us with the opportunity to reply. We hope that the following response addresses the issues raised and is helpful in further clarifying the impact of renal impairment on dipeptidyl peptidase-4 (DPP-4) inhibitors, as discussed in our manuscript.