• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Diabetes technology & therapeutics >The effects of depression on metabolic control and quality of life in indigent patients with type 2 diabetes.
【24h】

The effects of depression on metabolic control and quality of life in indigent patients with type 2 diabetes.

机译：抑郁症对2型糖尿病贫困患者代谢控制和生活质量的影响。

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: The objective of this study was to assess differences in metabolic control and health-related quality of life (QOL) among depressed and nondepressed adults in an indigent population with type 2 diabetes. RESEARCH DESIGN AND METHODS: Subjects completed validated surveys to assess depression and QOL. Depression was assessed with the Center for Epidemiological Studies-Depression Scale and defined as a score of > or =16. Metabolic control (hemoglobin A1C, total cholesterol, low-density lipoprotein [LDL] cholesterol, and high-density lipoprotein [HDL] cholesterol) measures were abstracted from medical records. We compared demographic characteristics, metabolic control, and QOL by depression status. Ordinary least squares regression was used to assess differences in QOL scores and metabolic control levels by depression status adjusting for covariates. RESULTS: In the study sample (n = 201), approximately 20% (n = 40) were depressed. In unadjusted analyses, subjects with depression had significantly lower SF-12 physical component summary (PCS) scores (30.4 +/- 7.3 vs. 39.6 +/- 11.8, P < 0.001) and mental component summary (MCS) scores (32.8 +/- 10.5 vs. 48.9 +/- 9.2, P < or = 0.001) and significantly higher total cholesterol (209.3 +/- 72.1 vs. 186.6 +/- 50.9, P = 0.024) compared to those without depression. No significant differences were observed by depression status in hemoglobin A1C, LDL cholesterol, and HDL cholesterol. After adjustment for relevant covariates, depressed individuals continued to have lower SF-12 PCS (36.1 vs. 39.0, P < or = 0.001) and MCS (41.6 vs. 46.8, P < or = 0.001) scores, but the difference in total cholesterol levels was no longer significant. CONCLUSIONS: In an indigent sample with type 2 diabetes, depression is significantly associated with decreased physical and mental components of QOL. This finding further reinforces the importance of addressing depression in all populations with type 2 diabetes.
机译：背景：本研究的目的是评估2型糖尿病贫困人群中抑郁和非抑郁成年人的代谢控制和健康相关生活质量（QOL）的差异。研究设计和方法：受试者完成了经过验证的调查，以评估抑郁和生活质量。抑郁症由流行病学研究中心-抑郁量表评估，并定义为>或= 16。从医疗记录中提取了代谢控制（血红蛋白A1C，总胆固醇，低密度脂蛋白[LDL]胆固醇和高密度脂蛋白[HDL]胆固醇）量度。我们通过抑郁状态比较了人口统计学特征，代谢控制和生活质量。普通最小二乘回归用于通过对协变量进行抑郁状态调整来评估QOL评分和代谢控制水平的差异。结果：在研究样本（n = 201）中，约有20％（n = 40）被压抑。在未经调整的分析中，患有抑郁症的受试者的SF-12身体成分摘要（PCS）得分（30.4 +/- 7.3对39.6 +/- 11.8，P <0.001）和精神成分摘要（MCS）得分（32.8 + / -10.5 vs. 48.9 +/- 9.2，P <或= 0.001），与没有抑郁症的人相比，总胆固醇显着更高（209.3 +/- 72.1 vs. 186.6 +/- 50.9，P = 0.024）。血红蛋白A1C，LDL胆固醇和HDL胆固醇的抑郁状态未观察到显着差异。在对相关协变量进行调整后，抑郁者的SF-12 PCS评分（36.1 vs. 39.0，P <或= 0.001）和MCS评分（41.6 vs. 46.8，P <或= 0.001）仍然较低，但总胆固醇差异水平不再重要。结论：在贫困的2型糖尿病样本中，抑郁症与QOL的身心组成显着相关。这一发现进一步强调了解决所有2型糖尿病人群中抑郁症的重要性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号