It has been >25 years since the clinical manifestations of aluminum ingestion from parenteral fluids were reported,1'2 Impaired bone growth, especially in adults, and delays in mental development in neonates are the predominant effects observed. Aluminum is ubiquitous, which unfortunately leads to its undesired presence in parenteral products. Of these parenteral products, parenteral nutrition (PN) is a substantial source of aluminum.3 Normally, aluminum is easily eliminated in the urine. Adult patients with renal compromise and neonates are the patient populations at greatest risk of developing toxicity from the aluminum present in parenteral fluids.
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